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HMOX1 — IL34

Text-mined interactions from Literome

Mizuno et al., Am J Pathol 2011 (Alzheimer Disease...) : IL-34 increased the expression of insulin degrading enzyme, aiding the clearance of oAß, and induced the antioxidant enzyme heme oxygenase-1 in microglia to reduce oxidative stress, without producing neurotoxic molecules
Lee et al., J Agric Food Chem 2013 (Diabetes Mellitus, Type 2) : It was found that monascin promoted heme oxygenase-1 (HO-1) expression mediated by Nrf2. Suppressions of AGEs, tumor necrosis factor-a (TNF-a), and interleukin-1ß ( IL-ß ) in serum of MG-induced rats were attenuated in the monascin administration group treated with retinoic acid ( RA )
Collino et al., Dis Model Mech 2013 (Disease Models, Animal...) : Besides, chronic HO-1 activation suppressed the elevated levels of myeloperoxidase (MPO) activity, interleukin 1ß (IL-1ß) production and tumor necrosis factor-a (TNFa) production that were evoked by the ischemic injury, and increased the plasma level of the anti-inflammatory cytokine IL-10
Das et al., J Antimicrob Chemother 2013 (Leishmaniasis, Visceral) : Furthermore, HO-1 blockade by miltefosine led to suppression of interleukin-10 and transforming growth factor-ß, but enhanced interleukin-12 and tumour necrosis factor-a production, in VL patients