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GAL — IRF6

Text-mined interactions from Literome

Simi et al., J Neurochem 2005 : We found that ( 1 ) LPS induced c-fos mRNA levels were sensitive to p38 mitogen activated protein kinase ( MAPK ) inhibitors but not to mitogen-activated/extracellular signal regulated kinase ( ERK ) or calcium-calmodulin dependent kinase inhibitors, ( 2 ) LPS activated both serum response element ( SRE ) and cyclic AMP/calcium response element ( CRE ) -driven luciferase reporters in transient transfection assays, ( 3 ) LPS induced the phosphorylation of Elk1 CRE binding protein ( CREB ) /activated transcription factor-1 (ATF-1) and the activation of GAL4-Elk1 and GAL4-CREB chimeric proteins, and ( 4 ) mutation of both SRE and CRE elements was necessary and sufficient to completely abolish LPS induction of a rat c-fos proximal promoter-luciferase reporter
Ait-Ali et al., Neuropharmacology 2010 : Messenger RNAs encoding vasoactive intestinal polypeptide (VIP) and galanin, both modulators of steroidogenesis in neighboring adrenal cortex, are up-regulated at 24 h ( eight-fold for VIP and two-fold for galanin ) after LPS injection, and remain elevated for the following 24 h. Up-regulation of VIP and galanin by LPS is abrogated in pituitary adenylate cyclase activating polypeptide ( PACAP ) -deficient mice, suggesting an interaction between LPS, or LPS induced cytokines, and PACAP released in adrenal medulla from the splanchnic nerve
Akachi et al., J Nutr Sci Vitaminol (Tokyo) 2010 (Carbon Tetrachloride Poisoning...) : Nobiletin, the most important compound in the n-hexane-soluble fraction, also had suppressive effects on liver injuries induced by carbon tetrachloride, acetaminophen and GalN/lipopolysaccharide (LPS) in addition to liver injury induced GalN
Amir et al., Cell Death Differ 2013 (Drug-Induced Liver Injury...) : GalN blocked LPS induction of hepatic autophagy, and increased autophagy from beclin 1 overexpression prevented GalN/LPS injury
Black et al., J Lipid Res 1983 (Drug-Induced Liver Injury...) : These abnormalities are presumed to result from hepatic injury alone, but the effect of GalN on intestinal Lps has not been studied ... GalN reduces apoE and C ( mainly of hepatic origin ) in d less than 1.006 g/ml gut Lps , which may contribute to the CM catabolic defect in GalN rats
Czaja et al., Am J Physiol 1994 : Hepatic MnSOD mRNA levels were not affected by GalN or GalN with LPS but were increased 13-fold by LPS alone