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CREM — PTH

Text-mined interactions from Literome

Liu et al., Bone 2007 (Bone Resorption) : We previously showed that PTH induces ICER ( inducible cAMP early repressor ) in osteoblasts
Tetradis et al., J Bone Miner Res 1998 : Parathyroid hormone induces expression of the inducible cAMP early repressor in osteoblastic MC3T3-E1 cells and mouse calvariae ... To investigate whether PTH induces ICER expression in osteoblastic cells, RNA from MC3T3-E1 cells was subjected to reverse transcriptase-polymerase chain reaction using primers spanning the ICER sequence ... In cultured mouse calvariae, PTH also induced ICER mRNA accumulation, which peaked at 2 h and returned almost to baseline by 10 h. Overexpression of ICER IIgamma decreased both baseline and PTH stimulated prostaglandin G/H synthase 2 promoter activity in MC3T3-E1 cells