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BMP4 — MSC
Text-mined interactions from Literome
Alfaro et al., J Biol Chem 2010
(Calcinosis...) :
sFRP2 suppression of
bone morphogenic protein ( BMP ) and Wnt signaling
mediates mesenchymal stem cell (MSC) self-renewal promoting engraftment and myocardial repair
Lee et al., Biochem Biophys Res Commun 2013
:
BMP4 exposure triggered FAK activation at pY397 auto-phosphorylation site in murine C3H10T1/2 MSCs. Interestingly, silencing FAK by small hairpin RNA ( shRNA ) significantly suppressed
BMP4 induction of
MSC adipogenic activities, including lipid accumulation and expression of key adipogenic genes ( C/EBPa, PPAR?, aP2 ), as relative to shRNA vector control