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SOCS1 — TLR7
Text-mined interactions from Literome
Bartz et al., Blood 2006
:
The results indicate that
TLR stimulation during the period of DC generation interferes with and deviates DC differentiation and that these effects are
mediated particularly by
SOCS-1
Tajiri et al., J Immunol 2012
(Autoimmune Diseases...) :
Suppressor of cytokine signaling
(SOCS) 1 plays a key role in the negative regulation of both
TLR- and cytokine receptor mediated signaling, which is involved in innate immunity and subsequent adaptive immunity