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CASP10 — IKBKB

Pathways - manually collected, often from reviews:

• KEGG RIG-I-like receptor signaling pathway: Complex of CASP10-CASP8 → Complex of CHUK-IKBKB-IKBKG (protein-protein, activation)
  
• Reactome Reaction: CASP10 → IKBKB (indirect_complex) Chaudhary et al., Oncogene 2000
• Reactome Reaction: CASP10 → IKBKB (reaction) Chaudhary et al., Oncogene 2000
• WikiPathways RIG-I-like Receptor Signaling: Complex of CASP8-CASP10 → Complex of IKBKG-CHUK-IKBKB (activation)
  

Text-mined interactions from Literome

Catley et al., Br J Pharmacol 2005 (Asthma) : IKK beta ( KA ) also reduced cell viability and induced caspase-3 and PARP cleavage regardless of the stimuli, indicating the induction of apoptosis
Chen et al., Crit Care Med 2007 (Burns...) : IKK blocks caspase 3 expression by up-regulating BCL-xL and cellular FLICE inhibitory protein expression
May et al., J Biol Chem 2007 : Surprisingly, death of IKKbeta-/- MEFs was not blocked by caspase inhibition, demonstrating that IKKbeta negatively regulates caspase independent cell death ( CICD )
Oh et al., J Pharmacol Exp Ther 2011 (Inflammation...) : In activated human mast cells, the receptor interacting protein 2 (RIP2), I?B kinase ( IKK ) -ß, nuclear factor-?B ( NF-?B ) /RelA, and caspase-1 activation were increased, but increased RIP2, IKK-ß , NF-?B/RelA, and caspase-1 activation were inhibited by the treatment of IPT