Pan et al., Cancer 2007
:
Also, TSA promoted Egr-1 expression, which is the main transcription factor of PTEN, and this resulted in up-regulation of PTEN expression, which consequently potentiated apoptosis
Yoshioka et al., J Biol Chem 2008
(Glioblastoma) :
TSA also increases the expression of transcription factors Sp-1 and Egr-1