Koltsova et al., J Immunol 2007
:
Id3 is presumably essential for traversal of the beta-selection checkpoint in this context because of the inability of other inhibitor of DNA binding family members to compensate, since transgenic Egr1 does not induce expression of inhibitor of DNA binding 1 (Id1) or 2 ( Id2 )
Subbaramaiah et al., J Biol Chem 2008
:
The ability of PGE ( 2 ) to activate Id-1 transcription was mediated by enhanced binding of Egr-1 to the Id-1 promoter
Passiatore et al., J Cell Physiol 2011
(Brain Neoplasms...) :
Induction of Id-1 by FGF-2 involves activity of EGR-1 and sensitizes neuroblastoma cells to cell death
Tournay et al., Mol Cell Biol 1996
:
On the basis of these findings, we propose that the regulation of the Id1 response to serum is mediated in part by the early response gene Egr-1 and as such provides a signaling link between the early-growth-response transcription factors and dominant negative helix-loop-helix proteins