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ATF4 — VIM
Text-mined interactions from Literome
Lian et al., J Biol Chem 2009
:
DNA cotransfection and gel retardation demonstrated that
vimentin inhibited the transactivation activity of
ATF4 on osteocalcin by preventing it to bind OSE1, the ATF4 binding site on the osteocalcin promoter
Lian et al., J Biol Chem 2012
:
Here we show that TGFß inhibits
ATF4 dependent activation of Ocn by up-regulation of
vimentin expression ... Interestingly, TGFß did not directly regulate the expression of ATF4 ; instead, it enhanced the expression of
vimentin , a negative
regulator of
ATF4 , at the post-transcriptional level