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TP53 — YBX1
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
-
IRef Biogrid Interaction:
YBX1
—
TP53
(direct interaction, pull down)
Kojic et al., J Mol Biol 2004*
-
IRef Biogrid Interaction:
YBX1
—
TP53
(direct interaction, pull down)
Okamoto et al., Oncogene 2000*
-
IRef Biogrid Interaction:
YBX1
—
TP53
(physical association, affinity chromatography technology)
Okamoto et al., Oncogene 2000*
-
IRef Biogrid Interaction:
YBX1
—
TP53
(physical association, affinity chromatography technology)
Tian et al., J Cell Physiol 2011*
-
IRef Hprd Interaction:
YBX1
—
TP53
(in vitro)
Okamoto et al., Oncogene 2000*, Mertens et al., J Biol Chem 2002*
-
IRef Hprd Interaction:
YBX1
—
TP53
(in vivo)
Okamoto et al., Oncogene 2000*, Mertens et al., J Biol Chem 2002*
-
IRef Intact Interaction:
Complex of 88 proteins
(association, tandem affinity purification)
Agrawal et al., Cell cycle (Georgetown, Tex.) 2010
-
IRef Ophid Interaction:
YBX1
—
TP53
(aggregation, interologs mapping)
Brown et al., Bioinformatics 2005
Text-mined interactions from Literome
Okamoto et al., Oncogene 2000
:
Gel mobility shift assays showed that the interaction of
YB-1 with p53
stimulated the sequence-specific DNA binding of
p53 to its consensus sequence
Zhang et al., Oncogene 2003
(Cell Transformation, Viral) :
Nuclear localization of Y-box factor
YB1 requires wild-type
p53 ... In this paper, we explore a
role for
p53 in the nuclear localization of
YB1
Lasham et al., J Biol Chem 2003
:
Using reporter assays we show that
YB1 represses transcription of the
p53 promoter in a sequence-specific manner ... We also show that
YB1 reduces endogenous levels of
p53 , which in turn reduces p53 activity
Homer et al., Oncogene 2005
:
We report that transcriptionally active
p53 is
required for nuclear localization of
YB1
Zhang et al., Yi Chuan 2006
(Neoplasms) :
It has been demonstrated that
YB-1 represses transcription of the
p53 promoter in a sequence-specific manner using specifically reporter assays
Sinnberg et al., Exp Dermatol 2012
(MAP Kinase Signaling System...) :
We show that the PI3K/AKT and
p53 signalling, growth factors and chemotherapeutic agents
increase YB-1 promoter activity