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IL17A — TLR3

Text-mined interactions from Literome

Kim et al., Immunol Lett 2007 (Arthritis, Rheumatoid...) : TLR stimulation of RA-FLS also induced the production of IL-1beta and TNF-alpha to a lesser extent ; however, it had no effect on IL-17 production
van Beelen et al., Immunity 2007 (Bacterial Infections...) : MDP enhanced obligate bacterial Toll-like receptor ( TLR ) agonist induction of IL-23 and IL-1, which promoted IL-17 expression in T cells
Tournadre et al., Arthritis Rheum 2010 (Dermatomyositis...) : Stimulation with interferon-gamma (IFNgamma) increased TLR-3 mRNA levels, but IL-17 down-regulated the inducing effect of IFNgamma
Cho et al., J Clin Invest 2010 (Staphylococcal Skin Infections) : Furthermore, IL-17 induction required IL-1, TLR2 , and IL-23 and was critical for host defense, since IL-17R-deficient mice had a phenotype similar to that of gammadelta T cell-deficient mice
Ather et al., J Immunol 2011 (Disease Models, Animal...) : CD4 ( + ) T cells polyclonally stimulated in the presence of conditioned media from SAA exposed DCs produced IL-17 , and the capacity of polyclonally stimulated splenocytes to secrete IL-17 is dependent upon IL-1, TLR2 , and the NLRP3 inflammasome
Kwok et al., Arthritis Res Ther 2012 (Sjogren's Syndrome) : The stimulation of TLR2, TLR4 and TLR6 additively induced the production of IL-17 and IL-23 from the PBMCs of pSS patients especially in the presence of TLR2 stimulation
van den Brand et al., Ann Rheum Dis 2013 (Arthritis, Experimental) : Systemically, TLR4 in both BM-derived and resident cells contributed to IL-17 production by splenic T-cells, whereas in the DLNs of arthritic joints this was not the case