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Birnbaum et al., Prostaglandins Other Lipid Mediat 2007
:
We assessed the effect of ASA on the myocardial production of 15-epi-LXA4 and PGI ( 2 ) after induction by lipopolysaccharide (LPS) or PIO+ATV ... ASA ( 50 mg/kg and 200 mg/kg, but not 10 mg/kg ) augmented the LPS effect on 15-epi-LXA4 but attenuated the effect on 6-keto-PGF ( 1alpha )
Chiang et al., J Pharmacol Exp Ther 1998
(Peritonitis) :
A cytochrome P450 inhibitor administered in the presence of ASA did not prevent 15-epi-LXA4 formation, which suggests that P450 does not significantly contribute to formation of 15-epi-LXA4 in this murine model