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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

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CDX2 — TCF20

Text-mined interactions from Literome

Guo et al., J Biol Chem 2004 (Colonic Neoplasms) : We report that Cdx1 or Cdx2 expression does inhibit beta-catenin/TCF transcriptional activity in colon cancer cells ... Finally, we show that colon cancer cells effectively reduce Cdx2 mediated inhibition of Wnt/beta-catenin/TCF transcriptional activity when compared with other model systems
Guo et al., Carcinogenesis 2010 (Colonic Neoplasms) : The intestine-specific transcription factor Cdx2 inhibits beta-catenin/TCF transcriptional activity by disrupting the beta-catenin-TCF protein complex ... Specifically, inhibition of beta-catenin/TCF activity by Cdx2 does not require Cdx2 transcriptional activity ... We identify a subdomain in the N-terminus that is highly conserved and when mutated significantly reduces Cdx2 inhibition of beta-catenin/TCF transcriptional activity