Stefansson et al., J Biol Chem 2001
:
The first is dependent on PAI-1 inhibition of proteinase activity, most likely chicken plasmin, while the second is independent of PAI-1 's anti-proteinase activity and instead appears to act through PAI-1 binding to vitronectin
Vial et al., Cancer cell international 2006
:
This positive regulation of PAI-1 on fibronectin assembly was independent of PAI-1 's anti-proteinase activity, but acted through PAI-1 binding to the somatomedin B domain of vitronectin