◀ Back to SAA1

MMP1 — SAA1

Text-mined interactions from Literome

O'Hara et al., Arthritis Rheum 2004 (Arthritis, Rheumatoid) : Recombinant human A-SAA induced both MMP-1 and MMP-3 secretion by FLS ... The mean fold increases in A-SAA induced MMP-1 and MMP-3 production were 2.6 and 10.6, respectively, compared with 7.6-fold and 41.9-fold increases in interleukin-1 beta induced MMP-1 and MMP-3 production
Mullan et al., Arthritis Rheum 2006 (Arthritis, Rheumatoid...) : A-SAA induced expression of VCAM-1, ICAM-1, and MMP-1 was down-regulated by NF-kappaB inhibition
Connolly et al., Arthritis Rheum 2012 (Arthritis, Rheumatoid...) : The effects of A-SAA on MMP/TIMP expression on RA fibroblast-like synoviocytes ( FLS ), primary human chondrocytes, and RA/psoriatic arthritis synovial explant cultures were assessed using real-time polymerase chain reaction, enzyme linked immunosorbent assay, antibody protein arrays, and gelatin zymography ... A-SAA increased MMP-1, MMP-3 , MMP-13, and MMP/TIMP expression in RA FLS and synovial explants ( P < 0.05 ) ... A-SAA increased MMP-1 , MMP-3, MMP-13, and MMP/TIMP expression in RA FLS and synovial explants ( P < 0.05 ) ... In chondrocytes, A-SAA induced MMP-1 , MMP-3, and MMP-13 messenger RNA and protein expression ( all P < 0.01 ), resulting in a significant shift in MMP : TIMP ratios ( P < 0.05 ) ... In chondrocytes, A-SAA induced MMP-1, MMP-3 , and MMP-13 messenger RNA and protein expression ( all P < 0.01 ), resulting in a significant shift in MMP : TIMP ratios ( P < 0.05 )
Strissel et al., Exp Cell Res 1997 : Role of serum amyloid A as an intermediate in the IL-1 and PMA stimulated signaling pathways regulating expression of rabbit fibroblast collagenase
Migita et al., Lab Invest 1998 (Arthritis, Rheumatoid) : When SAA containing media were immunodepleted by anti-SAA-specific antibody, SAA mediated MMP secretion was also abrogated