Li et al., J Cell Physiol 2006
(Leukemia, Myeloid, Acute...) :
Here we provide the first demonstration that the conditional expression of AML1-ETO by the ecdysone-inducible system dramatically increases the expression of connexin 43 (CX43) , together with growth arrest at G1 phase in leukemic U937 cells
Gao et al., Biochem Biophys Res Commun 2007
(Leukemia) :
In agreement, AML1-ETO overexpression in leukemic U937 cells activated c-Jun N-terminal kinase (JNK), while its specific inhibitor SP600125 effectively abrogated AML1-ETO induced Cx43 expression, indicating that JNK signaling pathway contributes to AML1-ETO induced Cx43 expression
Niger et al., J Bone Miner Res 2013
:
The regulation of runt related transcription factor 2 by fibroblast growth factor-2 and connexin43 requires the inositol polyphosphate/protein kinase Cd cascade