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PSMA5 — PSMD3
Pathways - manually collected, often from reviews:
-
BioCarta proteasome complex:
26S Proteasome complex (PSMD3-RPN2-PSMD4-PSMD12-PSMD11-PSMD14-RPN1-PSMA1-PSMA2-PSMA3-PSMA4-PSMA5-PSMA6-PSMA7-PSMB1-PSMB2-PSMB3-PSMB4-PSMB5-PSMB6-PSMB7)
→
None
(degradation, activates)
-
BioCarta proteasome complex:
26S Proteasome complex (PSMD3-RPN2-PSMD4-PSMD12-PSMD11-PSMD14-RPN1-PSMA1-PSMA2-PSMA3-PSMA4-PSMA5-PSMA6-PSMA7-PSMB1-PSMB2-PSMB3-PSMB4-PSMB5-PSMB6-PSMB7)
(degradation, activates)
-
BioCarta proteasome complex:
PA700 Activator complex (PSMD3-RPN2-PSMD4-PSMD12-PSMD11-PSMD14-RPN1)
→
26S Proteasome complex (PSMD3-RPN2-PSMD4-PSMD12-PSMD11-PSMD14-RPN1-PSMA1-PSMA2-PSMA3-PSMA4-PSMA5-PSMA6-PSMA7-PSMB1-PSMB2-PSMB3-PSMB4-PSMB5-PSMB6-PSMB7)
(modification, collaborate)
-
BioCarta proteasome complex:
PA700 Activator complex (PSMD3-RPN2-PSMD4-PSMD12-PSMD11-PSMD14-RPN1)
→
20S Proteasome complex (PSMA1-PSMB3-PSMB4-PSMB5-PSMB6-PSMB7-PSMA2-PSMA3-PSMA4-PSMA5-PSMA6-PSMA7-PSMB1-PSMB2)
(modification, collaborate)
-
BioCarta proteasome complex:
26S Proteasome complex (PSMD3-RPN2-PSMD4-PSMD12-PSMD11-PSMD14-RPN1-PSMA1-PSMA2-PSMA3-PSMA4-PSMA5-PSMA6-PSMA7-PSMB1-PSMB2-PSMB3-PSMB4-PSMB5-PSMB6-PSMB7)
→
20S Proteasome complex (PSMA1-PSMB3-PSMB4-PSMB5-PSMB6-PSMB7-PSMA2-PSMA3-PSMA4-PSMA5-PSMA6-PSMA7-PSMB1-PSMB2)
(modification, collaborate)
-
BioCarta proteasome complex:
PA700 Activator complex (PSMD3-RPN2-PSMD4-PSMD12-PSMD11-PSMD14-RPN1)
→
20S Proteasome complex (PSMA1-PSMB3-PSMB4-PSMB5-PSMB6-PSMB7-PSMA2-PSMA3-PSMA4-PSMA5-PSMA6-PSMA7-PSMB1-PSMB2)
(modification, collaborate)
-
BioCarta proteasome complex:
PA700 Activator complex (PSMD3-RPN2-PSMD4-PSMD12-PSMD11-PSMD14-RPN1)
→
Hybrid Proteasome complex (PSMA1-PSMB3-PSMB4-PSMB5-PSMB6-PSMB7-PSMD3-PSMD12-PSMD11-PSMA2-PSMD14-RPN1-RPN2-PSMD4-PSMA3-PSMA4-PSMA5-PSMA6-PSMA7-PSMB1-PSMB2)
(modification, collaborate)
-
BioCarta proteasome complex:
20S Proteasome complex (PSMA1-PSMB3-PSMB4-PSMB5-PSMB6-PSMB7-PSMA2-PSMA3-PSMA4-PSMA5-PSMA6-PSMA7-PSMB1-PSMB2)
→
Hybrid Proteasome complex (PSMA1-PSMB3-PSMB4-PSMB5-PSMB6-PSMB7-PSMD3-PSMD12-PSMD11-PSMA2-PSMD14-RPN1-RPN2-PSMD4-PSMA3-PSMA4-PSMA5-PSMA6-PSMA7-PSMB1-PSMB2)
(modification, collaborate)
-
Reactome Reaction:
PSMA5
→
PSMD3
(direct_complex)
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
-
IRef Biogrid Interaction:
PSMD3
—
PSMA5
(colocalization, biochemical)
Havugimana et al., Cell 2012
-
MIPS CORUM PA700-20S-PA28 complex:
PA700-20S-PA28 complex complex (PSMA1-PSMA2-PSMA3-PSMA4-PSMA5-PSMA6-PSMA7-PSMB1-PSMB2-PSMB3-PSMB4-PSMB5-PSMB6-PSMB7-PSMC1-PSMC2-PSMC3-PSMC4-PSMC5-PSMC6-PSMD1-PSMD10-PSMD11-PSMD12-PSMD13-PSMD14-PSMD2-PSMD3-PSMD4-PSMD5-PSMD6-PSMD7-PSMD8-PSMD9-PSME1-PSME2)
Kopp et al., J Mol Biol 2001
-
IRef Corum Interaction:
Complex of 37 proteins
(association, cosedimentation through density gradient)
Kopp et al., J Mol Biol 2001
-
IRef Hprd Interaction:
Complex of 901 proteins
(in vivo)
Hamazaki et al., EMBO J 2006
-
IRef Intact Interaction:
Complex of 46 proteins
(association, anti tag coimmunoprecipitation)
Yao et al., Mol Cell 2008
-
IRef Intact Interaction:
Complex of 40 proteins
(association, affinity chromatography technology)
Qiu et al., EMBO J 2006
-
IRef Intact Interaction:
Complex of 185 proteins
(association, cross-linking study)
Humphries et al., Science signaling 2009
-
IRef Intact Interaction:
Complex of 177 proteins
(association, cross-linking study)
Byron et al., Proteomics 2012
-
IRef Intact Interaction:
Complex of 222 proteins
(association, tandem affinity purification)
Koch et al., Cell cycle (Georgetown, Tex.) 2007
-
IRef Intact Interaction:
Complex of 203 proteins
(association, cross-linking study)
Byron et al., Proteomics 2012
-
IRef Intact Interaction:
Complex of 34 proteins
(association, anti tag coimmunoprecipitation)
Yao et al., Mol Cell 2008
-
IRef Intact Interaction:
Complex of 33 proteins
(association, anti tag coimmunoprecipitation)
Kaneko et al., Cell 2009
Text-mined interactions from Literome
Husom et al., Arch Biochem Biophys 2004
(Atrophy) :
These results suggest significant alterations in the intrinsic activity, the percentage of immunoproteasome, and the
regulation of the
20S proteasome by PA28 and
PA700 in aged muscle
Thompson et al., J Biol Chem 2009
:
Subcomplexes of
PA700 , the 19 S
regulator of the
26 S proteasome , reveal relative roles of AAA subunits in 26 S proteasome assembly and activation and ATPase activity