UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

◀ Back to PROC

PROC — PROS1

Pathways - manually collected, often from reviews:

BioCarta extrinsic prothrombin activation pathway: F Xa/TF/F VIIa complex (F3) → Protein C/Protein S complex (PROC-PROS1) (modification, activates)
BioCarta extrinsic prothrombin activation pathway: None → Protein C/Protein S complex (PROC-PROS1) (modification, activates)
BioCarta extrinsic prothrombin activation pathway: F V (F5) → Protein C/Protein S complex (PROC-PROS1) (modification, collaborate)
BioCarta intrinsic prothrombin activation pathway: Protein C/Protein S complex (PROC-PROS1) → blood-coagulation factor iia (F2) (modification, inhibits)
BioCarta intrinsic prothrombin activation pathway: Protein C/Protein S complex (PROC-PROS1) → F V (F5) (modification, inhibits)
KEGG Complement and coagulation cascades: Complex of PROC-PROS1 → F5 (protein-protein, inhibition)
KEGG Complement and coagulation cascades: Complex of PROC-PROS1 → F8 (protein-protein, inhibition)
KEGG Complement and coagulation cascades: A2M → Complex of PROC-PROS1 (protein-protein, inhibition)
KEGG Complement and coagulation cascades: SERPINA5 → Complex of PROC-PROS1 (protein-protein, inhibition)
KEGG Complement and coagulation cascades: Complex of PROC-PROS1 → F2 (protein-protein, inhibition)
Reactome Reaction: PROC → PROS1 (indirect_complex)

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

IRef Hprd Interaction: PROC — PROS1 (in vitro) Guglielmone et al., Thromb Haemost 1992 *, Ohlin et al., J Biol Chem 1988 *
IRef Ophid Interaction: PROC — PROS1 (aggregation, confirmational text mining) Ohlin et al., J Biol Chem 1988 *
IRef Ophid Interaction: PROC — PROS1 (aggregation, interologs mapping) Brown et al., Bioinformatics 2005