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PAPPA — SMC3

Text-mined interactions from Literome

Resch et al., Endocrinology 2006 (Carotid Artery Injuries...) : In this study, we used mice with targeted disruption of the pregnancy associated plasma protein-A gene ( PAPP-A-/- ) and wild-type ( WT ) littermates to test the hypotheses that PAPP-A , a metalloproteinase that cleaves inhibitory IGF binding protein (IGFBP)-4, regulates vascular SMC responses to IGF-I in vitro and is critical for the development of vascular neointima after injury in vivo
Bale et al., Am J Physiol Endocrinol Metab 2013 (Carotid Artery Injuries) : In this study, we used transgenic mice that constitutively express human PAPP-A in arterial smooth muscle to test the hypothesis that overexpression of PAPP-A enhances vascular smooth muscle cell ( SMC ) response to IGF-I in vivo