Gene interactions and pathways from curated databases and text-mining

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NTRK1 — PIK3R1

Pathways - manually collected, often from reviews:

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Nusser et al., J Biol Chem 2002 : Taken together, these data indicate that NGF mediated activation of TrkA receptor stimulates PI3K , which in turn increases Rac1 activity to induce transient RhoA inactivation during the initial phase of neurite outgrowth
Jin et al., Cancer Res 2007 (Cell Transformation, Neoplastic) : Here, we define some aspects of the molecular mechanisms regulating ETV6-NTRK dependent Ras-Erk1/2 and PI3K-Akt activation
Akpan et al., Brain Res 2008 (Chagas Disease) : It also requires TrkA dependent PI3K and MAPK/Erk signaling pathways because PDNF stimulation of cholinergic transcripts is abolished by specific pharmacological inhibitors
Roche et al., Proc Natl Acad Sci U S A 1994 : A second tyrosine kinase receptor , the epidermal growth factor receptor, also required the PI 3-K for efficient signaling