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APOA1 — NFYB
Text-mined interactions from Literome
Oleaga et al., Mol Nutr Food Res 2013
:
Cocoa flavanol metabolites activate HNF-3ß, Sp1, and
NFY mediated transcription of
apolipoprotein AI in human cells ... Incubation with 3-methyl-epicatechin led to an increase in HNF-3ß mRNA, HNF-3ß, ER-a, Sp1, and NFY protein levels and the activation of
ApoAI transcription
mediated by
NFY , Sp1, and ER-a
Novak et al., Biochem Biophys Res Commun 1997
:
Cotransfection of HepG2 cells with both the -177 to -148 apoA-I CAT constructs and plasmid expressing NFY alpha and NFY beta, transactivated the apoA-I promoter by 1.8 fold, indicating that
NFY is a positive
activator of the
apoA-I gene