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IL1A — MUC6

Text-mined interactions from Literome

Yoon et al., Acta Otolaryngol 1999 : The aim of this study was to examine whether TNF-alpha, IL-1beta or their combination can increase the secretion of mucin as an indicator of mucous secretion, the secretion of lysozyme as an indicator of serous secretion and the secretion of IL-6 and IL-8 as important cytokines
Imbert-Fernandez et al., Exp Eye Res 2011 : However with 24 h TNFa, MUC1/A increased IL-1ß and IL-8 whereas MUC1/B had no effect on cytokine expression
Jarry et al., Gut 1996 : The main findings include : ( a ) IL-1 stimulated a rapid release of mucin from filter grown HT29-C1.16E cells, this effect being dose related ; ( b ) this secretory effect was abolished in the presence of the blocking monoclonal antibody M4 specific for IL-1 receptors type I, showing that IL-1 receptors type I mediated IL-1 action ; ( c ) experiments based on chamber cultures showed that these receptors were located on the basolateral membranes of HT29-C1.16E cells ; ( d ) finally, mRNA for IL-1 receptors type I were detected by reverse transcriptase-polymerase chain reaction in these cells