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ALB — LRP2

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Hprd Interaction: LRP2 — ALB (in vivo) Brunskill et al., Am J Kidney Dis 2001*, Cui et al., Am J Physiol 1996*
• IRef Ophid Interaction: LRP2 — ALB (aggregation, interologs mapping) Brown et al., Bioinformatics 2005

Text-mined interactions from Literome

Bento-Abreu et al., J Neurochem 2008 : In addition, when the activity of megalin is blocked by specific antibodies or by silencing megalin with specific siRNA, albumin binding and internalization is strongly reduced indicating that megalin is required for albumin binding and internalization in the astrocyte
Bento-Abreu et al., J Neurochem 2009 : In this study, we show that the binding and internalization of albumin involve its interaction with megalin , caveolin-1, caveolin-2 and cavin, but not with clathrin in astrocytes from primary culture
Buchäckert et al., J Physiol 2012 : Moreover, gene silencing and pharmacological inhibition of the multi-ligand receptor megalin resulted in significantly decreased albumin binding and uptake in monolayers of primary alveolar type II and type I-like and cultured lung epithelial cells