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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

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JUN — RHOA

Text-mined interactions from Literome

Wroblewski et al., J Cell Sci 2003 (Neoplasm Invasiveness) : RhoA acted through activation of both NF-kappaB and AP-1 , whereas Rac activated NF-kappaB but not AP-1
Polk et al., Am J Physiol Cell Physiol 2007 (Nephritis) : In this study we employed normal rat kidney epithelial ( NRK52E ) cells to identify a novel LPS induced signaling pathway in which RhoA mediated AP-1 activity promotes expression of cyclooxygenase-2 (COX-2) with consequent feedback inhibition of NF-kappaB activation through IKKbeta