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ARSK — JUN

Text-mined interactions from Literome

Geleziunas et al., Nature 2001 : The interaction of Nef with ASK1 inhibits both Fas- and TNFalpha mediated apoptosis, as well as the activation of the downstream c-Jun amino-terminal kinase
Chang et al., Exp Cell Res 2002 : This suggests that IL-8 induction by LTbetaR is via TRAFs elicited signaling pathways, including NIK/IKK dependent NF-kappaB activation and ASK/MKK/JNK dependent AP-1 activation
Hwang et al., FEBS Lett 2002 : Cotransfection with ALG-2 resulted in the nuclear presence of ASK1 and inhibited the activation of c-Jun N-terminal kinase (JNK) by ASK1 in BOSC23 cells
Yamagishi et al., J Biochem 2003 : On the other hand, the expression of ASK1-DeltaN , a constitutively active form of ASK1, activated p38 and c-Jun , but not JNK, another possible downstream target of ASK1
Kumasawa et al., Eur J Pharmacol 2005 : The results showed that LTD ( 4 ) induced AP-1 activation determined by AP-1 dependent luciferase gene activity and ASK1 phosphorylation ... These results indicate that LTD ( 4 ) is capable of inducing AP-1 activation and ASK1 regulates AP-1 activation in LTD ( 4 ) -stimulated airway smooth muscle cells
Li et al., Crit Care Med 2005 : ASK1 inhibition with thioredoxin attenuated high tidal volume ventilation induced MIP-2 messenger RNA expression, MIP-2 protein production, neutrophil migration into the lung, airway epithelial cell apoptosis, activation of JNK, and AP-1 DNA binding
Hikoso et al., J Am Coll Cardiol 2007 (Disease Models, Animal...) : Inhibition of ASK1 reduced the number of apoptotic cells and selectively attenuated c-Jun NH2-terminal kinase activation
Yu et al., J Immunol 2009 : Furthermore, thrombin mediated AP-1 activation was inhibited by ASK1DN , JNK1/2DN, and SP600125
Gu et al., Oncogene 2009 : PIM1 phosphorylation of ASK1 on Ser83 inhibited ASK1 mediated c-Jun N-terminal kinase phosphorylation as well as p38 kinase phosphorylation
Seong et al., J Biol Chem 2010 : PDK1 functionally suppresses ASK1 mediated AP-1 transactivation and H ( 2 ) O ( 2 ) -mediated apoptosis in a kinase dependent manner
Liu et al., PloS one 2012 (MAP Kinase Signaling System) : CTGF mediated increase of NF-?B and AP-1 luciferase activity was inhibited by SB203580 and SP600125 or ASK1 shRNA or p38 and JNK mutant