Gene interactions and pathways from curated databases and text-mining

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IRF4 — REL

Pathways - manually collected, often from reviews:

Text-mined interactions from Literome

Grumont et al., J Exp Med 2000 : Rel induces interferon regulatory factor 4 (IRF-4) expression in lymphocytes : modulation of interferon regulated gene expression by rel/nuclear factor kappaB ... Here we show that mitogen induced expression of interferon (IFN) regulatory factor 4 ( IRF-4 ), a lymphoid-specific member of the IFN family of transcription factors, is Rel dependent
Shindo et al., Cytokine 2011 : We also demonstrated that IL-2 production was also enhanced by exogenously expressed IRF-4 and c-Rel in the presence of P/I, in T-cells, and that the optimal IL-2 and IL-4 productions in vivo was IRF-4 dependent using IRF-4-/- mice