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IL1B — IRF4
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Marecki et al., J Immunol 1999
:
Furthermore, both
IRF4 and ICSBP
activated transcription of the
IL-1beta promoter in both cell types
Marecki et al., J Immunol 2001
:
In macrophages, synergistic activation of
IL-1beta reporter gene expression was preferentially
mediated by
IRF-4 , whereas IRF-4 and ICSBP were equally capable of synergizing with PU.1 when coexpressed in fibroblasts ... Furthermore, coexpression of IRF-1 and IRF-2 dramatically increased the capacity of both
PU.1/IRF-4 and PU.1/ICSBP to
induce IL-1beta reporter gene expression in fibroblasts