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CD28 — IL3
Text-mined interactions from Literome
Okkenhaug et al., Nat Immunol 2001
:
Nonetheless, this mutated form of
CD28 still prevents the induction of anergy and
promotes T cell proliferation,
interleukin 2 secretion and B cell help
Fraser et al., Mol Cell Biol 1992
(Leukemia, T-Cell) :
Stimulation of
CD28 in the presence of TCR-like signals
increases the activity of the GM-CSF,
IL-3 , and IFN-gamma promoters by three- to sixfold
Abreu et al., Arthritis Res Ther 2010
(Arthritis, Experimental...) :
Ex vivo, Rac1 inhibitory peptide suppressed T-cell
receptor/CD28 dependent production of tumor necrosis factor alpha, interferon gamma and
interleukin-17 by T cells from collagen primed mice, and reduced induction of ICOS and CD154, T-cell costimulatory proteins important for B-cell help
Dumont et al., J Immunol 1998
:
FK506 also reduced
CD3/CD28 induced production of
IL-3 , IL-4, IL-10, TNF-alpha, and IL-6 but augmented that of GM-CSF, IL-5, IFN-gamma, and IL-13