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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

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DEFB4B — IL22

Text-mined interactions from Literome

Liu et al., J Invest Dermatol 2002 : Human beta-defensin-2 production in keratinocytes is regulated by interleukin-1 , bacteria, and the state of differentiation
Wolk et al., Immunity 2004 : In these cells, IL-22 activated STAT3 and directly and transcriptionally increased the expression of beta-Defensin 2 and beta-Defensin 3
Brand et al., Am J Physiol Gastrointest Liver Physiol 2006 (Crohn Disease...) : IL-22 significantly increased cell proliferation ( P = 0.002 ) and phosphatidylinsitol 3-kinase dependent IEC cell migration ( P < 0.00001 ) as well as mRNA expression of TNF-alpha, IL-8, and human beta-defensin-2
Liang et al., J Exp Med 2006 : IL-22 in conjunction with IL-17A or IL-17F synergistically induced the expression of beta-defensin 2 and S100A9 and additively enhanced the expression of S100A7 and S100A8