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EPHB4 — HOXA9
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Bruhl et al., Circ Res 2004
:
Because Eph receptor tyrosine kinases importantly contribute to angiogenesis, we examined whether
HoxA9 may transcriptionally
regulate the expression of
EphB4 ... Downregulation of
HoxA9 reduced the expression of
EphB4 ... Consistently,
HoxA9 wild-type overexpression
activated the
EphB4 promoter as determined by reporter gene expression
Diehl et al., Blood 2007
:
As a potential underlying mechanism, MLL siRNA down-regulated mRNA and protein levels of the
HoxA9 dependent axon guidance factor
EphB4