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HMGB1 — MYLIP
Text-mined interactions from Literome
Kanaan et al., Innate Immun 2013
(Chronic Disease...) :
TNF-a, regulated by miR-155 and miR-146a, was decreased in the LPS pretreated group at all time points ( P? < ?0.05 ), as were
HMGB1 , a key alarmin
regulated by
miR-146 , -142-3p, -299 and -200c ( P? < ?0.05 ), and IL-1ß and IL-6, both regulated by miR-132and miR-21 respectively ( P? < ?0.05 )
Hutchison et al., Glia 2013
:
Knockdown of miR-181
enhanced LPS induced production of pro-inflammatory cytokines ( TNF-a, IL-6, IL-1ß, IL-8 ) and
HMGB1 , while overexpression of
miR-181 resulted in a significant increase in the expression of the anti-inflammatory cytokine IL-10