◀ Back to GRK6
GRK6 — VIPR2
Text-mined interactions from Literome
Mahavadi et al., Regul Pept 2007
:
The aim of the study was to examine the mechanisms by which ACh, acting via m2 receptors, regulates
GRK2 mediated
VPAC(2) receptor desensitization in gastric smooth muscle cells
Murthy et al., Am J Physiol Cell Physiol 2008
:
Phosphorylation of GRK2 by PKA augments
GRK2 mediated phosphorylation, internalization, and desensitization of
VPAC2 receptors in smooth muscle ... These results demonstrate that in gastric smooth muscle
VPAC(2) receptor phosphorylation is
mediated by
GRK2 ... Phosphorylation of
GRK2 by PKA
enhances GRK2 activity and its ability to induce
VPAC(2) receptor phosphorylation, internalization, desensitization, and degradation