Gene interactions and pathways from curated databases and text-mining

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GATA3 — ICOS

Text-mined interactions from Literome

Yagi et al., J Immunol 2003 : We found a tight correlation among the levels of H4/inducible costimulator (ICOS) expression, IL-4 production, and GATA-3 induction , using activated CD4 ( + ) T cells obtained from six different murine strains ... In addition, retroviral expression of GATA-3 during the stimulation of naive CD4 ( + ) T cells from C57BL/6 or IL-4 ( -/- ) mice increased H4/ICOS expression on activated CD4 ( + ) T cells
Honkanen et al., Diabetes Metab Res Rev 2008 (Diabetes Mellitus, Type 1) : T-cell polarization and regulation related markers were analysed by quantitative reverse transcription polymerase chain reaction ( QRT-PCR ) ( Th1 promoting T-bet, Th2 promoting GATA-3 and regulation related FOXP3, ICOS and NFATc2 )