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FOXO3 — LRRK2
Text-mined interactions from Literome
Kanao et al., Hum Mol Genet 2010
(Nerve Degeneration) :
Activation of
FoxO by
LRRK2 induces expression of proapoptotic proteins and alters survival of postmitotic dopaminergic neuron in Drosophila
Kanao et al., PloS one 2012
(Neurodegenerative Diseases) :
Activation of the forkhead box transcription factor FoxO is suggested to be involved in dopaminergic ( DA ) neurodegeneration in a Drosophila model of Parkinson 's disease ( PD ), in which a PD gene product
LRRK2 activates FoxO through phosphorylation