We have a suspicion that you are an automated web bot software, not a real user. To keep our site fast for other users, we have slowed down this page. The slowdown will gradually disappear. If you think this is a mistake, please contact us at genome-www@soe.ucsc.edu. Also note that all data for hgGeneGraph can be obtained through our public MySQL server and all our software source code is available and can be installed locally onto your own computer. If you are unsure how to use these resources, do not hesitate to contact us.
UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

◀ Back to CDH16

CDH16 — HDAC2

Text-mined interactions from Literome

Yamaguchi et al., Cancer Sci 2010 (Gallbladder Neoplasms) : In TGBC2TKB cells, the expression of EZH2 and HDAC1/2 were decreased by SAHA treatment, and p16(INK4a), E-cadherin , and p21were simultaneously activated ; however, no such findings were obtained in HGECs, suggesting that the effect of SAHA depends on the EZH2 mediated tumor suppressor loss
Huang et al., Mol Pharmacol 2011 : This finding, together with the HDAC inhibitor induced up-regulation of KLF4 and E-cadherin , suggests that HDAC inhibitors could activate the expression of these genes through changes in histone methylation status
Iordache et al., International journal of molecular sciences 2012 : RT-PCR assay showed that HDAC inhibitors down-regulated the expression of endothelial genes such as VE-cadherin , CD133, CXCR4 and Tie-2