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AKT2 — CAPN11

Text-mined interactions from Literome

Box et al., Biochim Biophys Acta 2010 (Anoxia) : Interestingly, inhibitors of proteosome, calpain or caspase mediated proteolysis did not significantly block AKT loss
Queiroz et al., PloS one 2012 (Leukemia) : Pro-death activity of violacein is actually carried out by inhibition of calpain and DAPK1 and activation of PKA, AKT and PDK, followed by structural changes caused by endoplasmic reticulum stress and Golgi apparatus collapse, leading to cellular demise
Wang et al., Cardiovasc Res 2013 : Blocking AKT further increased doxorubicin induced cardiac injuries, suggesting the effects of calpain inhibition may be mediated by inactivating the AKT signalling
Briz et al., J Neurosci 2013 : BDNF treatment increased phosphorylation of both Akt and ERK, but only the effect on Akt was blocked by calpain inhibition
Hollborn et al., PloS one 2013 : The cytotoxic effect of curcumin involved activation of caspase-3 and calpain , intracellular calcium signaling, mitochondrial permeability, oxidative stress, increased phosphorylation of p38 MAPK and decreased phosphorylation of Akt protein