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AKT1 — MAP3K1

Text-mined interactions from Literome

Johnson et al., Urology 2002 (Prostatic Neoplasms) : Calcitriol induces poly ( adenosine diphosphate-ribose ) polymerase cleavage, increases bax/bcl-2 ratio, reduces levels of phosphorylated mitogen activated protein kinases ( P-MAPKs ; also known as extracellular signal related kinase [ ERK] 1/2 ) and phosphorylated Akt , induces caspase dependent mitogen activated protein kinase kinase ( MEK ) cleavage and upregulation of MEK kinase-1 , all potential markers of the apoptotic pathway
Bild et al., Oncogene 2002 : AKT overexpression also prevented the cleavage of endogenous MEKK1 by genotoxins
Han et al., Oncogene 2006 : Induction of Nur77 nuclear export by MEKK1 required a prolonged MEKK1 activation and was attenuated by Akt activation