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UCSC Genome Browser Gene Interaction Graph
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Gene interactions and pathways from curated databases and text-mining
◀ Back to PPP1CA
PPP1CA — SMAD7
Pathways - manually collected, often from reviews:
NCI Pathway Database ALK1 signaling events :
PPP1CA (PPP1CA)
→
SMAD7 (SMAD7)
(modification, collaborate)
Valdimarsdottir et al., BMC cell biology 2006
physical interaction
NCI Pathway Database ALK1 signaling events :
SMAD7 (SMAD7)
→
TGFB1/TGFBR2/Endoglin/TGFBR1/ALK1/PPP1CA complex (TGFBR2-TGFBR1-ACVRL1-PPP1CA-ENG-TGFB1)
(modification, activates)
Valdimarsdottir et al., BMC cell biology 2006
physical interaction
NCI Pathway Database TGF-beta receptor signaling :
PPP1CA (PPP1CA)
→
TGFB/TGFBR2/TGFBR1/SMAD7/GADD34 complex (TGFBR1-SMAD7-PPP1R15A-TGFBR2)
(modification, collaborate)
Bennett et al., Nat Genet 2002 , Shi et al., J Cell Biol 2004
mutant phenotype, assay, physical interaction, other species
NCI Pathway Database TGF-beta receptor signaling :
PPP1CA (PPP1CA)
→
TGFB/TGFBR2/TGFBR1/SMAD7/GADD34/PPP1CA complex (TGFBR1-SMAD7-PPP1R15A-PPP1CA-TGFBR2)
(modification, collaborate)
Bennett et al., Nat Genet 2002 , Shi et al., J Cell Biol 2004
mutant phenotype, assay, physical interaction, other species
NCI Pathway Database TGF-beta receptor signaling :
TGFB/TGFBR2/TGFBR1/SMAD7/GADD34 complex (TGFBR1-SMAD7-PPP1R15A-TGFBR2)
→
TGFB/TGFBR2/TGFBR1/SMAD7/GADD34/PPP1CA complex (TGFBR1-SMAD7-PPP1R15A-PPP1CA-TGFBR2)
(modification, collaborate)
Bennett et al., Nat Genet 2002 , Shi et al., J Cell Biol 2004
mutant phenotype, assay, physical interaction, other species
NCI Pathway Database TGF-beta receptor signaling :
SARA (ZFYVE9)
→
TGFB/TGFBR2/TGFBR1/SMAD7/GADD34/PPP1CA complex (TGFBR1-SMAD7-PPP1R15A-PPP1CA-TGFBR2)
(modification, activates)
Bennett et al., Nat Genet 2002 , Shi et al., J Cell Biol 2004
mutant phenotype, assay, physical interaction, other species
Reactome Reaction :
PPP1CA
→
SMAD7
(reaction)
Shi et al., J Cell Biol 2004
Reactome Reaction :
PPP1CA
→
SMAD7
(indirect_complex)
Shi et al., J Cell Biol 2004