Gene interactions and pathways from curated databases and text-mining

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CXCL10 — IL22

Text-mined interactions from Literome

Hosokawa et al., J Periodontal Res 2009 (Periodontitis) : However, interleukin-4 and interleukin-13 inhibited CXCL10 production by interferon-gamma stimulated or tumor necrosis factor-alpha-stimulated-human gingival fibroblasts ... On the other hand, interleukin-17A and interleukin-22 enhanced CXCL10 production by human gingival fibroblasts treated with interferon-gamma and inhibited CXCL10 production by tumor necrosis factor-alpha stimulated human gingival fibroblasts
Tousi et al., Neurosci Lett 2012 (Parkinson Disease) : a-Synuclein potentiates interleukin-1ß induced CXCL10 expression in human A172 astrocytoma cells
Bachmann et al., Biochem Pharmacol 2013 : Accordingly, only after IFNa pre-incubation was IL-22 induced STAT1 binding to the CXCL10 promoter detectable ... Using the viral mimic polyinosinic : polycytidylic acid and the IFNa/ß antagonist B18R we furthermore demonstrate the capability of endogenous IFN to promote IL-22 induced STAT1 activation and expression of CXCL10