We have a suspicion that you are an automated web bot software, not a real user. To keep our site fast for other users, we have slowed down this page. The slowdown will gradually disappear. If you think this is a mistake, please contact us at genome-www@soe.ucsc.edu. Also note that all data for hgGeneGraph can be obtained through our public MySQL server and all our software source code is available and can be installed locally onto your own computer. If you are unsure how to use these resources, do not hesitate to contact us.
UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining
NOTCH3: top 25 interacting genes (chr19:15269848-15311806)
Mouse over or click genes or lines for details. Dashed lines indicate interactions without text mining support. Click any gene to make it the new center. Click any line to show details about the interaction. Only NOTCH3-interacting genes and only the most-mentioned/most-curated interactions are shown in the graph. See the Help Page for details.
Gene:               Hide non-NOTCH3 interactions     Show top Genes on graph    

Less-frequently mentioned interactions with NOTCH3, not among the Top 25
Other genes interacting with NOTCH3. Mouse-over to show number of abstracts or databases. Sorted by article count (sort alphabetically).
Like above, interactions are colored by support. Grey:only text mining, light-blue:interaction database, blue:pathway database

AKT1 ▸ DTX1 ▸ AKT2 ▸ HEY1 ▸ CEBPZ ▸ MAML1 ▸ HES3 ▸
AKT3 ▸ HES2 ▸ NCSTN ▸ BMP1 ▸ RELA ▸ HES4 ▸ HES6 ▸
NFKB1 ▸ ADAM17 ▸ MYLIP ▸ ADAM10 ▸ LFNG ▸ TCF23 ▸ TCF7 ▸
MAPK10 ▸ TCF21 ▸ TCF15 ▸ MAPK8 ▸ TCF12 ▸ MAPK3 ▸ MAPK11 ▸
MAPK6 ▸ PSEN2 ▸ TCF24 ▸ MAPK9 ▸ CDKN1A ▸ MAPK13 ▸ BMP2 ▸
TCF20 ▸ BMP4 ▸ MAPK7 ▸ DLL3 ▸ TCF4 ▸ NOTCH4 ▸ TCF25 ▸
MAPK1 ▸ MAPK15 ▸ MAPK14 ▸ SLC22A3 ▸ TCF19 ▸ MAPK4 ▸ MAPK12 ▸
TCF3 ▸ MAML2 ▸ MAML3 ▸ BMP15 ▸ BMP7 ▸ SMC3 ▸ BMP10 ▸
NEUROG3 ▸ SMC5 ▸ PTBP1 ▸ BMP6 ▸ BMP5 ▸ BMP3 ▸ SMC2 ▸
MESP2 ▸ FGF2 ▸ SMC4 ▸ FBXW7 ▸ SMC6 ▸ SOX2 ▸ CDH1 ▸
APH1A ▸ PIEZO1 ▸ VEGFA ▸ IRF6 ▸ NRARP ▸ ADAM12 ▸ HNRNPF ▸
APH1B ▸ HDAC1 ▸ CDH2 ▸ IFNG ▸ ASCL1 ▸ FGF4 ▸ FLT1 ▸
STAT3 ▸ FGF1 ▸ PTCRA ▸ PTBP2 ▸ HNRNPH1 ▸ SMN1 ▸ TP53 ▸
CDH8 ▸ FGF16 ▸ SMAD4 ▸ CDH15 ▸ ADAM9 ▸ ADAM28 ▸ EFNB2 ▸
FGF7 ▸ FGF12 ▸ ADAM7 ▸ CDH6 ▸ SETD2 ▸ RBP4 ▸ FGF19 ▸
ADAM32 ▸ CDH23 ▸ ADAM23 ▸ IL12A ▸ FGF21 ▸ CDH9 ▸ HLA-DRB1 ▸
ADAM8 ▸ ADAM29 ▸ EGFR ▸ FGF10 ▸ CDH24 ▸ ADAM20 ▸ CDH22 ▸
CCND1 ▸ CD8A ▸ CDH5 ▸ FGF13 ▸ ADAM30 ▸ PCNA ▸ CDH4 ▸
ADAM22 ▸ EPHB2 ▸ PTHLH ▸ GATA2 ▸ FGF18 ▸ FGF11 ▸ CDH13 ▸
FGF9 ▸ TBX6 ▸ FGF17 ▸ FGF20 ▸ FGF6 ▸ ADAM15 ▸ ADAM2 ▸
FGF22 ▸ ATOH1 ▸ CISH ▸ CDH12 ▸ CDH7 ▸ CTNNB1 ▸ CDH10 ▸
CDH18 ▸ ATP5O ▸ CDH11 ▸ ADAM6 ▸ CDH17 ▸ MSI1 ▸ POFUT1 ▸
ADAM5 ▸ ADAM21 ▸ MYC ▸ MET ▸ ADAM18 ▸ ADAM33 ▸ FOXP3 ▸
FGF23 ▸ CDH20 ▸ ADAM19 ▸ CDH3 ▸ FGF8 ▸ CDH16 ▸ FGF3 ▸
RUNX2 ▸ CDH26 ▸ FGF14 ▸ CD4 ▸ EGF ▸ NODAL ▸ IL12B ▸
ADAM11 ▸ FGF5 ▸ CDH19 ▸ PROX1 ▸ ABL1 ▸ TLR6 ▸ TLR1 ▸
MSX2 ▸ UROD ▸ SKP2 ▸ TLR2 ▸ EYA1 ▸ TLR8 ▸ FOXC2 ▸
SOX8 ▸ RALA ▸ NFATC1 ▸ NES ▸ APEH ▸ TSC1 ▸ SNAI1 ▸
CXCR4 ▸ PDLIM7 ▸ TGFB3 ▸ DYRK1A ▸ MTOR ▸ HLA-DRA ▸ DUSP1 ▸
IL10 ▸ HDAC2 ▸ POGLUT1 ▸ PTCH1 ▸ RBBP7 ▸ GSK3B ▸ GAL ▸
MSI2 ▸ TLR9 ▸ ACD ▸ HIF1A ▸ IL4 ▸ TLR7 ▸ SHH ▸
SGCG ▸ MMP9 ▸ ERBB2 ▸ CDKN1B ▸ TNF ▸ SOX9 ▸ TLR4 ▸
RBBP4 ▸ SOX21 ▸ FLT4 ▸ SIRT1 ▸ RRAS ▸ KLF4 ▸ HIF1AN ▸
SMAD5 ▸ MFNG ▸ SMAD2 ▸ TLR5 ▸ TLR10 ▸ ID3 ▸ JUN ▸
TGFB1 ▸ HEY2 ▸ GATA3 ▸ ITCH ▸ TWIST1 ▸ SPEN ▸ ID2 ▸
TLR3 ▸ PARP1 ▸ TSLP ▸ SMAD3 ▸ TSC2 ▸ ICK ▸ SOX1 ▸
MBS1 ▸ UBA52 ▸ NOLC1 ▸ ATP1A1 ▸ NAT10 ▸ NOC2L ▸ INTS6 ▸
HSPA5 ▸ EEF1A1 ▸ LRPPRC ▸ SLC25A10 ▸ STT3A ▸ MSH6 ▸ RHOT2 ▸
PSMA1 ▸ RPS27L ▸ PRKDC ▸ DDX41 ▸ NUP98 ▸ RHOT1 ▸ ITGB1 ▸
IMPA1 ▸ ZFYVE20 ▸ ZNF300 ▸ SLC25A5 ▸ ALPI ▸ ANKRD28 ▸ LBR ▸
SLC25A3 ▸ ZBED4 ▸ TRRAP ▸ CHUK ▸ HADHA ▸ DDB1 ▸ INTS5 ▸
AKAP8 ▸ DHX33 ▸ MYO1C ▸ DDX21 ▸ CLASP1 ▸ SLC25A6 ▸ MYBBP1A ▸
SLC27A4 ▸ TRIM23 ▸ DOCK8 ▸ UBC ▸ PMM1 ▸ PCLO ▸ SLC16A3 ▸
RFC1 ▸ MYO1B ▸ FBLN1 ▸ CCDC9 ▸ STRAP ▸ CTNNA1 ▸ ZNF148 ▸
ACADS ▸ E2F3 ▸ GPR116 ▸ KRT1 ▸ KAT2A ▸ NCK1 ▸ NUMA1 ▸
HSPA6 ▸ KRT14 ▸ TECR ▸ DHCR7 ▸ EFTUD2 ▸ MRPL57 ▸ NCAPG ▸
DVL2 ▸ DVL3 ▸ SMPD4 ▸ NDUFS1 ▸ MSH2 ▸ AFG3L2 ▸ ENOX2 ▸
ETV6 ▸ HSPA9 ▸ NCL ▸ PGAP1 ▸ DHX9 ▸ SEC61A1 ▸ ZC3H11A ▸
LRP1 ▸ SMARCA1 ▸ SLC25A4 ▸ DTX3L ▸ DSPP ▸ NUP93 ▸ NUP205 ▸
TFRC ▸ RAB13 ▸ SFMBT1 ▸ HELLS ▸ TCERG1 ▸ AHCTF1 ▸ SCD ▸
FURIN ▸ ATAD3A ▸ ATP2A2 ▸ MATR3 ▸ WRN ▸ L3MBTL3 ▸ ALB ▸
TCF7L2 ▸ GPAM ▸ TNXB ▸ CPT1A ▸ SHOC2 ▸ CSNK2B ▸ DVL1 ▸
IMMT ▸ SP1 ▸ SUN2 ▸ TRIM28 ▸ NPLOC4 ▸ SNW1 ▸ SLC2A1 ▸
GPD2 ▸ RBPJL ▸ RPS3 ▸ HLTF ▸ HNRNPU ▸ INTS3 ▸ POLG ▸
TMEM33 ▸ AGPAT5 ▸ KRT9 ▸ GTPBP2 ▸ LMNA ▸

Data information
Please see the Gene Interactions Track Manual.