Gene interactions and pathways from curated databases and text-mining
IRF6: top 25 interacting genes (chr1:209958961-209979487)
Mouse over or click genes or lines for details. Dashed lines indicate interactions without text mining support. Click any gene to make it the new center. Click any line to show details about the interaction. Only IRF6-interacting genes and only the most-mentioned/most-curated interactions are shown in the graph. See the Help Page for details.
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Less-frequently mentioned interactions with IRF6, not among the Top 25
Other genes interacting with IRF6. Mouse-over to show number of abstracts or databases. Sorted by article count (sort alphabetically).
Like above, interactions are colored by support. Grey:only text mining, light-blue:interaction database, blue:pathway database

MAPK6 ▸ MAPK7 ▸ IFNG ▸ EPHB2 ▸ NFKBIA ▸ NOS1 ▸ CCL2 ▸
CD14 ▸ ICAM1 ▸ IL4 ▸ JUN ▸ CPOX ▸ IL18 ▸ IL2 ▸
NOS3 ▸ IL5 ▸ IL13 ▸ FOS ▸ PTBP1 ▸ HNRNPF ▸ PTBP2 ▸
HNRNPH1 ▸ IL15 ▸ IL33 ▸ IL3 ▸ IL21 ▸ IL32 ▸ IL37 ▸
IL19 ▸ IL7 ▸ IL24 ▸ IL20 ▸ IL22 ▸ IL9 ▸ IL31 ▸
IL16 ▸ IL11 ▸ IL27 ▸ IL26 ▸ IL25 ▸ IL34 ▸ TLR2 ▸
CSF2 ▸ MMP9 ▸ AKT1 ▸ AKT2 ▸ AKT3 ▸ SYT1 ▸ AHSA1 ▸
CASP1 ▸ CASP3 ▸ CXCL10 ▸ CASP4 ▸ CASP8 ▸ CASP6 ▸ CASP9 ▸
CASP14 ▸ CASP7 ▸ CASP16 ▸ CASP10 ▸ CASP2 ▸ CASP12 ▸ CASP5 ▸
VCAM1 ▸ IFNB1 ▸ IL1RN ▸ GRAP2 ▸ RNF19A ▸ UMOD ▸ WNK1 ▸
LBP ▸ SELE ▸ TLR3 ▸ TLR9 ▸ HMOX1 ▸ CCL3 ▸ TLR1 ▸
CFP ▸ ANXA6 ▸ VEGFA ▸ TLR7 ▸ TLR6 ▸ CRK ▸ LANCL1 ▸
TLR8 ▸ TLR5 ▸ GPI ▸ CD86 ▸ STAT1 ▸ TLR10 ▸ MMP2 ▸
CD79A ▸ CD40 ▸ MMP1 ▸ HMGB1 ▸ MPO ▸ NOX1 ▸ CHUK ▸
ITGAM ▸ IKBKB ▸ CD80 ▸ POLDIP2 ▸ STAT3 ▸ IRF3 ▸ MMP3 ▸
MYD88 ▸ NOX4 ▸ MIP ▸ TP63 ▸ MMP13 ▸ MUC1 ▸ NOX5 ▸
NOX3 ▸ MUC2 ▸ MMP8 ▸ CA2 ▸ TGFB1 ▸ MMP14 ▸ MMP12 ▸
MUC7 ▸ IRAK1 ▸ MMP11 ▸ CXCL1 ▸ MMP16 ▸ MMP10 ▸ MMP15 ▸
MMP27 ▸ MMP26 ▸ MUC4 ▸ MMP21 ▸ CXCL2 ▸ CD46 ▸ MMP17 ▸
MMP25 ▸ RABEPK ▸ MUC16 ▸ MMP28 ▸ MMP19 ▸ MMP20 ▸ MMP24 ▸
MMP7 ▸ IKBKG ▸ MUC20 ▸ MUC8 ▸ TCF21 ▸ CXCL9 ▸ TCF4 ▸
TCF19 ▸ TCF23 ▸ MUC21 ▸ MUC6 ▸ MUC12 ▸ MUC19 ▸ MUC13 ▸
TCF25 ▸ MUC17 ▸ TCF15 ▸ TCF3 ▸ TCF12 ▸ TCF7 ▸ TCF24 ▸
TCF20 ▸ MUC15 ▸ MUC22 ▸ CTR9 ▸ HLA-DRA ▸ CXCL11 ▸ PAF1 ▸
LYZ ▸ CXCL12 ▸ LEO1 ▸ WDR61 ▸ CDC73 ▸ SERPINE1 ▸ HLA-DRB1 ▸
CXCL13 ▸ CXCL5 ▸ PLA2G4A ▸ PTGS1 ▸ LEP ▸ IRF1 ▸ IRAK4 ▸
MIPEP ▸ SOD3 ▸ CXCL6 ▸ SOD2 ▸ SOD1 ▸ C1orf228 ▸ CSF3 ▸
CXCL16 ▸ ITGB2 ▸ PGF ▸ CXCL14 ▸ PI3 ▸ CXCL17 ▸ IDO1 ▸
IL23A ▸ CXCL3 ▸ REL ▸ PIK3R1 ▸ HDC ▸ CRH ▸ PIK3CA ▸
HGF ▸ PDCD11 ▸ EGR1 ▸ SOCS3 ▸ CSF1 ▸ SAA1 ▸ CD83 ▸
MYLIP ▸ SLC25A10 ▸ IRAK3 ▸ PLA2G1B ▸ LTB ▸ ICAM4 ▸ NM ▸
ICAM3 ▸ ICAM2 ▸ NANOS2 ▸ ICAM5 ▸ MUC5AC ▸ INS ▸ IRAK2 ▸
ARG1 ▸ FAS ▸ NUP43 ▸ SLPI ▸ EDN1 ▸ MIF ▸ IGF1 ▸
CCR2 ▸ SETD2 ▸ SOAT1 ▸ CEBPB ▸ PTGES ▸ TNFSF11 ▸ BPI ▸
CD4 ▸ TBCE ▸ TNPO1 ▸ CREB5 ▸ FASLG ▸ DUSP1 ▸ NCF1 ▸
CREB1 ▸ CREB3 ▸ CCL4 ▸ CEBPA ▸ HDAC1 ▸ CAT ▸ IRF7 ▸
DEFB4B ▸ PTX3 ▸ SRC ▸ ARF1 ▸ S100A12 ▸ IRF2 ▸ MDM1 ▸
ARF5 ▸ CCL20 ▸ MDM4 ▸ SELP ▸ IFI44 ▸ CRP ▸ MAP3K8 ▸
ARF6 ▸ HDAC2 ▸ MDM2 ▸ ARF4 ▸ ARF3 ▸ CD69 ▸ IRF4 ▸
PPARG ▸ ARG2 ▸ PLD3 ▸ PLG ▸ GP9 ▸ PLD4 ▸ TNFRSF11B ▸
PLD6 ▸ RAC1 ▸ PLD1 ▸ GP2 ▸ MTOR ▸ PLD5 ▸ HIF1A ▸
CCR7 ▸ NGF ▸ GP6 ▸ PLD2 ▸ NFKBIB ▸ IRF8 ▸ RHOA ▸
APOE ▸ SLC17A5 ▸ ABCC1 ▸ CISH ▸ RBBP4 ▸ GP5 ▸ CD40LG ▸
TRAF6 ▸ APOB ▸ BAX ▸ PGD ▸ NOD2 ▸ CCR5 ▸ AVP ▸
AGTR2 ▸ SERPINB2 ▸ CDCA5 ▸ CCL5 ▸ PRKCA ▸ ALB ▸ TREM1 ▸
IL17D ▸ ZFP36 ▸ ADAM11 ▸ TIMP1 ▸ CCND1 ▸ HBD ▸ AHR ▸
SP1 ▸ BDNF ▸ GIT2 ▸ PPARA ▸ JAK2 ▸ CORT ▸ APC ▸
MAPKAPK2 ▸ BCL2 ▸ GJA1 ▸ CAV1 ▸ LITAF ▸ IL2RA ▸ TBK1 ▸
SELL ▸ ODC1 ▸ PDE4B ▸ LCN2 ▸ LY96 ▸ ATF2 ▸ ATP5O ▸
FCER2 ▸ LTF ▸ STS ▸ IFNA4 ▸ CALM3 ▸ IL1R1 ▸ HSPG2 ▸
BCL10 ▸ EGFR ▸ CXCR4 ▸ RBBP7 ▸ IRF9 ▸ LYN ▸ PLAU ▸
LPL ▸ LIF ▸ F3 ▸ IRF5 ▸ GNRH1 ▸ PRDX2 ▸ MLYCD ▸
SAP30 ▸ TFPI ▸ RAF1 ▸ CYP3A ▸ AGTR1 ▸ SAP130 ▸ SPP1 ▸
P2RX7 ▸ GDNF ▸ MOCOS ▸ HSPD1 ▸ SIN3A ▸ PARP1 ▸ PTK7 ▸
MNAT1 ▸ PRL ▸ NA ▸ TNFSF13B ▸ CSRP1 ▸ EIF2AK2 ▸ BCL3 ▸
CCR6 ▸ PTK6 ▸ MT3 ▸ ATP8A2 ▸ TNFSF10 ▸ CD2 ▸ BTK ▸
ARID4B ▸ NCF2 ▸ ADM ▸ CCR3 ▸ SLC27A5 ▸ SUDS3 ▸ SOCS1 ▸
IL17A ▸ IFNA2 ▸ UCN ▸ PTK2 ▸ GAL ▸ CCR9 ▸ LIPA ▸
CD8A ▸ IFNA8 ▸ TP53 ▸ RELB ▸ IFNA16 ▸ ACE ▸ IFNA1 ▸
MSH3 ▸ CCR10 ▸ ADAM17 ▸ ECM2 ▸ CD276 ▸ MAP3K14 ▸ TGFB2 ▸
IFNA21 ▸ ETS2 ▸ IFNA13 ▸ CCR4 ▸ IKBKAP ▸ CEL ▸ CSE ▸
ECM1 ▸ CCR1 ▸ IFNA14 ▸ JAK1 ▸ ACP2 ▸ IFNA7 ▸ PRG2 ▸
PRG4 ▸ NOTCH1 ▸ IFNA17 ▸ SPHK1 ▸ RETN ▸ FGB ▸ LDLR ▸
IFNA10 ▸ IFNA5 ▸ SETBP1 ▸ IFNA6 ▸ STAT5A ▸ NEDD9 ▸ CCR8 ▸
CEBPD ▸ IL2RB ▸ SLC22A3 ▸ NLRP3 ▸ PHKA2 ▸ MAP2K1 ▸ CXCR1 ▸
CRAT ▸ GCHFR ▸ MOK ▸ PRG3 ▸ CD44 ▸ APP ▸ TRAM2 ▸
CD55 ▸ MAF ▸ NOTCH3 ▸ EDN2 ▸ TRAM1 ▸ PLAUR ▸ PLIN2 ▸
MSH6 ▸ TNP2 ▸ GIF ▸ TXN ▸ WAS ▸ TNP1 ▸ ALG1 ▸
NEU1 ▸ MSH4 ▸ OCLN ▸ CXCR2 ▸ CADM1 ▸ ABCA1 ▸ EIF4EBP1 ▸
TYK2 ▸ CAMP ▸ SERPING1 ▸ SYK ▸ PTPN11 ▸ RAC2 ▸ HDAC3 ▸
TNFRSF1A ▸ CRYGEP ▸ BCL6 ▸ APCS ▸ ABCB1 ▸ NOD1 ▸ CCL24 ▸
PAM ▸ OLR1 ▸ UCP2 ▸ C9orf3 ▸ SLCO6A1 ▸ TF ▸ CAV3 ▸
ATF3 ▸ PCBD1 ▸ S100A8 ▸ IGFBP3 ▸ SIGLEC7 ▸ BCL9 ▸ ANXA1 ▸
MSH2 ▸ SAA4 ▸ GHR ▸ TGFB3 ▸ F2RL1 ▸ LTA ▸ BCL5 ▸
TNFRSF1B ▸ CNR2 ▸ FBXO32 ▸ SAA2 ▸ NOTCH4 ▸ NOTCH2 ▸ EDN3 ▸
SH3D19 ▸ THBD ▸ HDAC11 ▸ F2R ▸ MSH5 ▸ GPX3 ▸ CYP2B6 ▸
RPTOR ▸ S12 ▸ NPY4R ▸ FXR1 ▸ CD28 ▸ MET ▸ ELAVL1 ▸
EIF4E ▸ PRKAB1 ▸ UPK3B ▸ NEU4 ▸ PRKAA2 ▸ CNP ▸ AQP5 ▸
CEBPZ ▸ TFRC ▸ GPX2 ▸ CD8B ▸ ALPI ▸ SMC5 ▸ MTA2 ▸
GIT1 ▸ GSK3B ▸ COA6 ▸ CDH13 ▸ VIPR1 ▸ ACO1 ▸ GPX8 ▸
PRKAG2 ▸ SEC14L2 ▸ SMC6 ▸ PLAT ▸ CHD4 ▸ PLTP ▸ PRKAG1 ▸
GAST ▸ MARCKS ▸ A2M ▸ VIP ▸ PRKAA1 ▸ TRAF1 ▸ ADCY9 ▸
ITGAX ▸ MRXS5 ▸ SMC2 ▸ TSPO ▸ HP ▸ TYR ▸ JUND ▸
GPX4 ▸ CAV2 ▸ CD1A ▸ BIRC3 ▸ FADD ▸ PRKAB2 ▸ SLC2A1 ▸
PLCG1 ▸ GATA3 ▸ OXTR ▸ PTX4 ▸ CDC42 ▸ MT4 ▸ PGC ▸
CETP ▸ CD19 ▸ FPR1 ▸ COA4 ▸ SLC7A2 ▸ CD38 ▸ GPX1 ▸
GFAP ▸ CTSB ▸ GPX6 ▸ CYBB ▸ ARC ▸ MAP3K7 ▸ FGFR3 ▸
CIITA ▸ PGP ▸ SMC4 ▸ JAK3 ▸ S11 ▸ AGXT ▸ ACHE ▸
ANXA5 ▸ SMC3 ▸ HMGCR ▸ TECR ▸ UBL3 ▸ LPO ▸ COA1 ▸
NEU3 ▸ NAALADL1 ▸ TOLLIP ▸ LOX ▸ DDIT3 ▸ STX1A ▸ CX3CL1 ▸
GATA2 ▸ CES1 ▸ CCND2 ▸ SCARB1 ▸ NEU2 ▸ POU2F2 ▸ JUNB ▸
COA5 ▸ NPPA ▸ HDAC6 ▸ CTLA4 ▸ PRDX1 ▸ FXR2 ▸ EPB42 ▸
POMC ▸ S7 ▸ WNT2 ▸ CTRL ▸ COA3 ▸ SIGIRR ▸ GPX5 ▸
CCL18 ▸ ICOSLG ▸ PPARGC1A ▸ IFIT2 ▸ ISG15 ▸ DDX58 ▸ GPX7 ▸
IL18BP ▸ MCM7 ▸ TPGS2 ▸ NPY ▸ CTNNB1 ▸ NCOR1 ▸ PKD2 ▸
LTC4S ▸ AQP8 ▸ IL1R2 ▸ MEPE ▸ HSP90AA1 ▸ CAPN14 ▸ CLDN1 ▸
NR4A1 ▸ AQP2 ▸ C1QB ▸ USP7 ▸ GSR ▸ CAPN1 ▸ INSR ▸
ITGB1 ▸ TUBGCP2 ▸ HDAC9 ▸ KLK3 ▸ RIPK2 ▸ SP100 ▸ PLCG2 ▸
KHSRP ▸ EPB41 ▸ RPS6KB1 ▸ MLST8 ▸ PTEN ▸ ISG20 ▸ IFN1@ ▸
PARP10 ▸ CNR1 ▸ FCGR1A ▸ SERPINB6 ▸ SLC11A2 ▸ MBD3 ▸ MARCO ▸
TBL1XR1 ▸ HDAC7 ▸ PARP6 ▸ PRKAR1B ▸ PRKAR1A ▸ CLU ▸ NPR1 ▸
ADCY6 ▸ PPP2R2B ▸ GALT ▸ TXNRD2 ▸ ADAMTS5 ▸ CAPN13 ▸ ERP29 ▸
PMPCB ▸ NTF3 ▸ TPGS1 ▸ MT-CYB ▸ NCF4 ▸ S1PR1 ▸ IL2RG ▸
VDR ▸ PARP3 ▸ GPS2 ▸ BDKRB1 ▸ C4BPA ▸ PKD3 ▸ PPARD ▸
FST ▸ NTRK1 ▸ TPO ▸ CADM4 ▸ IDS ▸ BCAP31 ▸ IRG1 ▸
RSAD2 ▸ RHOB ▸ LAMP1 ▸ F12 ▸ TRIM63 ▸ AMBP ▸ MAP2K6 ▸
MUC5B ▸ CX3CR1 ▸ AKT1S1 ▸ PDCD1LG2 ▸ MAP2K3 ▸ PARP4 ▸ FEV ▸
GATA1 ▸ FGF2 ▸ CAPN12 ▸ EPS8 ▸ PARP8 ▸ ADCY1 ▸ HCLS1 ▸
LAMP2 ▸ ACSL1 ▸ SMN1 ▸ IL6R ▸ MCM3 ▸ APOA1 ▸ GATA4 ▸
PRDM1 ▸ CAPN7 ▸ CD9 ▸ KCNH4 ▸ SLC5A1 ▸ PLEK ▸ ERF ▸
CD5 ▸ SDC4 ▸ ASS1 ▸ AQP4 ▸ CD58 ▸ PKD1 ▸ C5AR1 ▸
LAMP3 ▸ PARP2 ▸ TIMP3 ▸ CCL4L2 ▸ CROT ▸ LAMP5 ▸ MCS ▸
PARP12 ▸ OSM ▸ PRDX5 ▸ ERP44 ▸ ADCY10 ▸ CAPN6 ▸ PRTN3 ▸
PDGFB ▸ RNPEP ▸ QRICH1 ▸ ADCY3 ▸ CAPN11 ▸ LGALS3 ▸ SPAG8 ▸
PTHLH ▸ MCM6 ▸ DST ▸ FOSL1 ▸ TPX2 ▸ CAPN3 ▸ SREBF1 ▸
MCM4 ▸ PARP15 ▸ PPP2R1A ▸ LGALS1 ▸ PPP2CA ▸ KCNMA1 ▸ FPR2 ▸
CYP1A1 ▸ GLA ▸ SDC2 ▸ PLN ▸ FGF21 ▸ GATA6 ▸ MCM2 ▸
HDAC10 ▸ G6PD ▸ PRX ▸ GATA5 ▸ NQO1 ▸ AGT ▸ CAPN9 ▸
IL13RA1 ▸ PARP11 ▸ RHO ▸ ADCY8 ▸ DOK3 ▸ CES3 ▸ VWF ▸
TAT ▸ CES2 ▸ MAL ▸ IGH ▸ SIRT1 ▸ BCR ▸ EPS15 ▸
ESAM ▸ CYP4F3 ▸ HDAC8 ▸ WNT5A ▸ PECAM1 ▸ MAP2K2 ▸ MCOLN1 ▸
HDAC4 ▸ PDCD2 ▸ IL1RAP ▸ CAPN10 ▸ PARP9 ▸ TFAP2A ▸ RASIP1 ▸
CAPN8 ▸ ETS1 ▸ NDUFAB1 ▸ ACAN ▸ TNFSF13 ▸ PGR ▸ SST ▸
P2RX4 ▸ PLA2G7 ▸ MTA1 ▸ ADCY2 ▸ HPGDS ▸ CAPN15 ▸ SMAD7 ▸
ADCY5 ▸ REG3A ▸ S1PR3 ▸ CORO2A ▸ MTDH ▸ CYP4F2 ▸ CYP1A2 ▸
QRICH2 ▸ PRKACB ▸ PRKACG ▸ FGF9 ▸ CYP4F11 ▸ CYP4F22 ▸ NANOS1 ▸
CAPN2 ▸ FOXP3 ▸ SLC9A1 ▸ PRKCB ▸ ABL1 ▸ PVR ▸ PIR ▸
KLF4 ▸ PRKAR2B ▸ TBL1X ▸ FMR1 ▸ C1QA ▸ KITLG ▸ NFKBIZ ▸
MCM5 ▸ EDNRA ▸ S100A9 ▸ PRKAR2A ▸ MST1R ▸ CPP ▸ MICE ▸
SPHK2 ▸ ERP27 ▸ HAMP ▸ ELANE ▸ CADM2 ▸ CTSL ▸ PARP16 ▸
ITGAL ▸ LRP1 ▸ SMAD4 ▸ CYP4F12 ▸ CYP4F8 ▸ CD1D ▸ ADCY4 ▸
NR1I2 ▸ PARP14 ▸ AQP1 ▸ USP14 ▸ CPZ ▸ CADM3 ▸ HDAC5 ▸
ADCY7 ▸ STAR ▸ CAPN5 ▸ PDGFA ▸ CCL1 ▸ IKBKE ▸ ARHGAP29 ▸
GPS1 ▸ CDK4 ▸ BNC2 ▸ ZBTB3 ▸ CREBBP ▸ COPS2 ▸ COPS4 ▸
NR3C1 ▸ UBC ▸ TLX2 ▸ PCAF ▸ COPS6 ▸ MID1 ▸ ONECUT1 ▸
SMARCD1 ▸ GTF2A1 ▸ COPS5 ▸ TAF1 ▸ GTF2E1 ▸ GTF3A ▸ RFX3 ▸
Data information
Please see the Gene Interactions Track Manual.