Gene interactions and pathways from curated databases and text-mining
IL8: top 25 interacting genes
Mouse over or click genes or lines for details. Dashed lines indicate interactions without text mining support. Click any gene to make it the new center. Click any line to show details about the interaction. Only IL8-interacting genes and only the most-mentioned/most-curated interactions are shown in the graph. See the Help Page for details.
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Less-frequently mentioned interactions with IL8, not among the Top 25
Other genes interacting with IL8. Mouse-over to show number of abstracts or databases. Sorted by article count (sort alphabetically).
Like above, interactions are colored by support. Grey:only text mining, light-blue:interaction database, blue:pathway database

TLR4 ▸ TLR2 ▸ FOS ▸ IL4 ▸ IL2 ▸ CSF2 ▸ IL17A ▸
TLR3 ▸ ICAM1 ▸ NM ▸ TLR5 ▸ CD40 ▸ PTGS2 ▸ IL13 ▸
VEGFA ▸ AHSA1 ▸ TLR9 ▸ TLR1 ▸ CA2 ▸ CCL2 ▸ IL3 ▸
TLR7 ▸ TLR8 ▸ IL15 ▸ TLR6 ▸ RNF19A ▸ IL5 ▸ IL33 ▸
TGFB1 ▸ TLR10 ▸ LTA ▸ NOS2 ▸ TCF4 ▸ TCF21 ▸ F2RL1 ▸
IL18 ▸ TCF24 ▸ IL22 ▸ TCF23 ▸ TCF3 ▸ TCF20 ▸ TCF19 ▸
TCF15 ▸ TCF25 ▸ TCF7 ▸ TCF12 ▸ CRK ▸ PIK3CA ▸ PIK3R1 ▸
CSE ▸ NA ▸ NFKBIA ▸ MMP9 ▸ IL1RN ▸ IL32 ▸ LPA ▸
GRAP2 ▸ WDR61 ▸ LEO1 ▸ PAF1 ▸ APOB ▸ EGF ▸ CDC73 ▸
CTR9 ▸ HGF ▸ IL31 ▸ MMP2 ▸ IL7 ▸ IL11 ▸ CXCR1 ▸
S100A8 ▸ IFNB1 ▸ IL9 ▸ FGF2 ▸ ITGAM ▸ IL25 ▸ IL20 ▸
IL19 ▸ IL16 ▸ IL21 ▸ IL26 ▸ IL37 ▸ IL24 ▸ INS ▸
FAS ▸ MMP3 ▸ IL27 ▸ POLDIP2 ▸ SAA1 ▸ IL34 ▸ EGFR ▸
NOS1 ▸ MIF ▸ PI3 ▸ CRP ▸ AKT3 ▸ AKT1 ▸ ALB ▸
CXCR2 ▸ AKT2 ▸ CALM3 ▸ MMP13 ▸ MMP1 ▸ IKBKB ▸ CASP4 ▸
CASP3 ▸ NOX1 ▸ CD14 ▸ F2R ▸ CASP16 ▸ CASP2 ▸ CASP7 ▸
CASP14 ▸ NOS3 ▸ CASP10 ▸ CASP12 ▸ NOX4 ▸ CASP1 ▸ CASP6 ▸
CASP8 ▸ CASP5 ▸ CD40LG ▸ CASP9 ▸ PTX3 ▸ NOX5 ▸ PLG ▸
HMGB1 ▸ NOX3 ▸ CHUK ▸ PTK7 ▸ SELE ▸ MYD88 ▸ PTK6 ▸
MYLIP ▸ TNFSF10 ▸ TGFB2 ▸ ITGB2 ▸ LIF ▸ PTK2 ▸ IGF1 ▸
NOD1 ▸ PRG4 ▸ GP5 ▸ MUC1 ▸ SRC ▸ PRG2 ▸ GP9 ▸
IL12B ▸ PRG3 ▸ GP2 ▸ MMP8 ▸ PTX4 ▸ STAT3 ▸ MAP3K7 ▸
LEP ▸ TREM1 ▸ GP6 ▸ ERVK-6 ▸ CXCL12 ▸ IKBKG ▸ IFNA2 ▸
IFNA1 ▸ IFNA14 ▸ IFNA4 ▸ SOD3 ▸ IL12A ▸ S100A12 ▸ SOD1 ▸
LTB ▸ PRKACG ▸ MMP14 ▸ PRKACB ▸ PAM ▸ PRKAR1A ▸ PTBP1 ▸
IFNA5 ▸ PLD2 ▸ SERPINE1 ▸ IFNA13 ▸ SOD2 ▸ IFNA6 ▸ PRKAR2B ▸
HNRNPF ▸ PRKAR1B ▸ HDAC2 ▸ HNRNPH1 ▸ MMP7 ▸ CSF3 ▸ IFNA7 ▸
WNK1 ▸ MPO ▸ VIP ▸ IFNA21 ▸ IFNA16 ▸ IFNA10 ▸ VCAM1 ▸
IFNA17 ▸ CRH ▸ PRKAR2A ▸ PTBP2 ▸ IFNA8 ▸ MMP24 ▸ CXCL10 ▸
EGR1 ▸ MSH3 ▸ MMP20 ▸ NOD2 ▸ MMP11 ▸ MMP25 ▸ MMP27 ▸
MMP21 ▸ SETD2 ▸ MMP15 ▸ PLD1 ▸ EDN1 ▸ ELANE ▸ MMP10 ▸
IL1R1 ▸ HDAC1 ▸ CAT ▸ FGF1 ▸ MMP26 ▸ TGFB3 ▸ CCL3 ▸
MMP19 ▸ MMP17 ▸ MMP28 ▸ MMP12 ▸ TNFRSF1A ▸ MMP16 ▸ CSK ▸
SPP1 ▸ ANGPT2 ▸ MSH5 ▸ MSH2 ▸ TRAF6 ▸ FASLG ▸ AHR ▸
CD4 ▸ PLD6 ▸ PLD4 ▸ PLD3 ▸ MSH4 ▸ NAALADL1 ▸ CD8A ▸
PLD5 ▸ PLA2G1B ▸ FGF7 ▸ QRICH1 ▸ TAB1 ▸ QRICH2 ▸ SYT1 ▸
MAP2K1 ▸ SST ▸ MSH6 ▸ STX2 ▸ FGF6 ▸ SOCS3 ▸ NGF ▸
PPARG ▸ FGF10 ▸ HDAC5 ▸ FGF8 ▸ FGF14 ▸ SELP ▸ HSPD1 ▸
PDLIM7 ▸ SELL ▸ FGF18 ▸ P2RY6 ▸ LTF ▸ HDAC3 ▸ RAC1 ▸
FGF22 ▸ SAA2 ▸ FGF3 ▸ FGF21 ▸ FGF20 ▸ FGF12 ▸ STAT1 ▸
FGF23 ▸ TNFSF12 ▸ CD46 ▸ FGF13 ▸ FGF16 ▸ FGF17 ▸ HDAC6 ▸
CD28 ▸ C1QB ▸ CXCL1 ▸ CSF1 ▸ CD38 ▸ FGF19 ▸ ETS1 ▸
FGF4 ▸ HMOX1 ▸ ADIPOQ ▸ C1QA ▸ FGF11 ▸ CSRP1 ▸ FGF9 ▸
ITGB1 ▸ FGF5 ▸ TXN ▸ TNFSF13B ▸ HSPG2 ▸ CD79A ▸ MUC12 ▸
PPARA ▸ SETBP1 ▸ MUC21 ▸ MUC4 ▸ HDAC7 ▸ MUC13 ▸ AGTR2 ▸
RHO ▸ PF4 ▸ ECM1 ▸ MUC2 ▸ STX1A ▸ CR1 ▸ IL2RA ▸
MUC20 ▸ HES1 ▸ MUC15 ▸ MUC7 ▸ CISH ▸ GPI ▸ MTX1 ▸
HDAC9 ▸ TRPV1 ▸ HSPB1 ▸ SAA4 ▸ CXCR3 ▸ TAT ▸ TNMD ▸
PDCD11 ▸ MUC17 ▸ APC ▸ STAT4 ▸ HDAC8 ▸ RBBP7 ▸ CD8B ▸
BCL3 ▸ NAP1L4 ▸ CPOX ▸ HDAC4 ▸ PRTN3 ▸ HDAC10 ▸ RBBP4 ▸
HDAC11 ▸ ECM2 ▸ RHOA ▸ PRKCD ▸ MTOR ▸ MUC8 ▸ MUC22 ▸
MUC6 ▸ PLAU ▸ ANG ▸ MUC16 ▸ ST8SIA2 ▸ PLA2G4A ▸ CFTR ▸
MUC19 ▸ ITIH4 ▸ CXCR4 ▸ ANGPT1 ▸ NPS ▸ PDGFB ▸ UTP15 ▸
NUP43 ▸ UTP6 ▸ APEX1 ▸ BCL10 ▸ PRR19 ▸ DUSP1 ▸ FCGR1A ▸
HES3 ▸ PRR13 ▸ PRKAB1 ▸ ICAM2 ▸ PRL ▸ TAC4 ▸ CXCL9 ▸
MAP3K1 ▸ IBD4 ▸ AZU1 ▸ MPL ▸ IBD9 ▸ CXCL6 ▸ MT4 ▸
HES7 ▸ PRR14 ▸ DDIT3 ▸ PRKAA2 ▸ HES6 ▸ ICAM5 ▸ IL17F ▸
DEFA1 ▸ MET ▸ ARG2 ▸ ADAM17 ▸ PRR3 ▸ ADCYAP1 ▸ LPL ▸
PRR15 ▸ FOXO3 ▸ UTP20 ▸ UTP18 ▸ UTP3 ▸ ELF4 ▸ ESR1 ▸
CCL20 ▸ PRKAA1 ▸ FGG ▸ MUC5AC ▸ HES2 ▸ JAK2 ▸ IL1R2 ▸
PRDX2 ▸ PRR25 ▸ PRR18 ▸ CXCL11 ▸ PRR24 ▸ IRAK3 ▸ HES5 ▸
ICOSLG ▸ IBD8 ▸ UTP23 ▸ TAC3 ▸ TPO ▸ ICAM3 ▸ EMD ▸
TGFA ▸ PGD ▸ IRAK1 ▸ RNASE3 ▸ ETS2 ▸ PRR7 ▸ PAEP ▸
TP53 ▸ CCR5 ▸ ICAM4 ▸ ADAM11 ▸ IBD2 ▸ EPO ▸ PRR12 ▸
IFI44 ▸ MAP2K7 ▸ GRP ▸ IBD7 ▸ PRR22 ▸ RELB ▸ PRR21 ▸
SMAD3 ▸ BCL2 ▸ PRR9 ▸ HDC ▸ PRKAG2 ▸ PRKAB2 ▸ FGA ▸
CHI3L1 ▸ BRAF ▸ A2M ▸ CYP1A1 ▸ TAC1 ▸ PRR11 ▸ IBD3 ▸
CTNNB1 ▸ SELPLG ▸ CXCL17 ▸ RENBP ▸ PRKAG1 ▸ PRR5 ▸ HBEGF ▸
IBD6 ▸ IBD5 ▸ NR0B1 ▸ PRR4 ▸ PRR26 ▸ PTAFR ▸ NTS ▸
PKD1 ▸ PRR16 ▸ NR4A2 ▸ TF ▸ SIGLEC7 ▸ SEA ▸ PRKCA ▸
ELF3 ▸ ARG1 ▸ CALM1 ▸ HES4 ▸ MT3 ▸ ROCK2 ▸ CALM2 ▸
OSM ▸ TFPI ▸ PGF ▸ NR4A1 ▸ PITX1 ▸ CAPN15 ▸ PAK6 ▸
FUT9 ▸ CP ▸ MYO10 ▸ TMSB4X ▸ FUT1 ▸ REL ▸ HCG15 ▸
SMAD4 ▸ PAK3 ▸ RAG1 ▸ SMAD5 ▸ FUT2 ▸ PDCD4 ▸ DNASE1 ▸
RAC3 ▸ HCG25 ▸ HCG26 ▸ CXCL14 ▸ MYO6 ▸ KLRB1 ▸ PTPN11 ▸
THBD ▸ FOXO4 ▸ DUOX1 ▸ UCN2 ▸ VAV1 ▸ IL23A ▸ CX3CL1 ▸
CAPN6 ▸ TNP2 ▸ HCG8 ▸ PARK7 ▸ TNFRSF9 ▸ CCL5 ▸ WNT1 ▸
NPY4R ▸ CAPN13 ▸ HCG17 ▸ WNT6 ▸ JAK3 ▸ FXYD1 ▸ VDR ▸
CD163 ▸ ATP8A2 ▸ ELF1 ▸ PAH ▸ HCG16 ▸ APOA2 ▸ HCG14 ▸
MTA1 ▸ ELF2 ▸ BCL6 ▸ PAK2 ▸ RNASE2 ▸ IFIH1 ▸ TSC22D3 ▸
SFXN1 ▸ HCG9 ▸ MAP2K4 ▸ OXA1L ▸ KDR ▸ TNFSF11 ▸ FGB ▸
PAK4 ▸ CGN ▸ IGF2 ▸ DPM2 ▸ MYO16 ▸ PAK1 ▸ FCER2 ▸
HCG18 ▸ FUT6 ▸ MEFV ▸ FGFR2 ▸ GRB10 ▸ PARK2 ▸ SMAD2 ▸
CAPN9 ▸ NPY6R ▸ CNR2 ▸ PDGFA ▸ CD44 ▸ RABEPK ▸ MKNK1 ▸
POU2F1 ▸ DDX58 ▸ CAPN11 ▸ CTGF ▸ PTPN22 ▸ GRB2 ▸ GH1 ▸
HCG24 ▸ GSTM1 ▸ FCGR2B ▸ CA1 ▸ TNFRSF1B ▸ SPESP1 ▸ ALX1 ▸
GRB7 ▸ CXCR6 ▸ CXCL5 ▸ CPB1 ▸ CD86 ▸ CDC42 ▸ GHRH ▸
PROK1 ▸ WNT16 ▸ C1orf228 ▸ HBD ▸ GIP ▸ NLRP3 ▸ TRNAI1 ▸
CCL4 ▸ SYK ▸ F10 ▸ MAP2K3 ▸ CEACAM1 ▸ DNASE2 ▸ CD83 ▸
ADAM19 ▸ AREG ▸ FUT8 ▸ KLK3 ▸ TACR1 ▸ ROCK1 ▸ ARSA ▸
SERPINE2 ▸ PTHLH ▸ HMGB2 ▸ FUT4 ▸ CXCL3 ▸ ALX3 ▸ KSR2 ▸
CAPN3 ▸ CXCL13 ▸ RETN ▸ SCARB1 ▸ MBP ▸ MYO19 ▸ FMR1 ▸
CAPN14 ▸ STAT5A ▸ CAPN12 ▸ BCR ▸ CDH5 ▸ CAPN5 ▸ HCG11 ▸
CNR1 ▸ SERPINB2 ▸ MAP2K5 ▸ BPI ▸ FOSL1 ▸ SMAD1 ▸ CSH1 ▸
SMAD6 ▸ FOXO1 ▸ ANPEP ▸ HCG20 ▸ SLPI ▸ ADM ▸ ADAM10 ▸
AGTR1 ▸ TEC ▸ BMP2 ▸ BLM ▸ CEBPB ▸ HLA-DRB1 ▸ TNP1 ▸
C3 ▸ FOXO6 ▸ HCG27 ▸ CD69 ▸ FOXP3 ▸ TRAF2 ▸ MPG ▸
PTGS1 ▸ ASIP ▸ NPY ▸ VASP ▸ ACKR3 ▸ ABL1 ▸ MTA3 ▸
CD2 ▸ S100A9 ▸ TPT1 ▸ HRH1 ▸ JAK1 ▸ CXCL16 ▸ MAP2K2 ▸
CAPN2 ▸ SMAD7 ▸ HCG23 ▸ KRT10 ▸ F2RL2 ▸ CEACAM6 ▸ MEPE ▸
ALX4 ▸ AR ▸ HMGB3 ▸ VCP ▸ HCG4 ▸ CAPN8 ▸ PGP ▸
CPB2 ▸ WNT3 ▸ HIF1A ▸ PAK7 ▸ CTSB ▸ MAPKAPK2 ▸ CSTA ▸
NAMPT ▸ FUT7 ▸ GAL ▸ CD1D ▸ F7 ▸ ITGA5 ▸ CYP1A2 ▸
WNT2 ▸ CAPN7 ▸ HCG22 ▸ MTA2 ▸ CAPN10 ▸ CDH1 ▸ HMGB4 ▸
ELF5 ▸ DEFA1B ▸ ELAVL1 ▸ TNPO1 ▸ DPM3 ▸ IRS1 ▸ MAP2K6 ▸
NFKBIZ ▸ APOE ▸ CEBPA ▸ CAPN1 ▸ WNT4 ▸ CSH2 ▸ ALOX5 ▸
GRB14 ▸ HCG21 ▸ DPM1 ▸ CYP19A1 ▸ RAC2 ▸ GAST ▸ CXCL2 ▸
APOA1 ▸ WNT11 ▸ MRXS5 ▸ SMAD9 ▸ FUT3 ▸ IDO1 ▸ FUT5 ▸
FUT11 ▸ FUT10 ▸ PINK1 ▸ SOAT1 ▸ CTSS ▸ GRPR ▸ LBP ▸
HRAS ▸ SPP2 ▸ TBP ▸ GPER1 ▸ HEBP1 ▸ TAS2R5 ▸ HCAR1 ▸
MCHR2 ▸ CCL27 ▸ GNAI2 ▸ CCL16 ▸ OXGR1 ▸ CCR10 ▸ CX3CR1 ▸
ADRA2B ▸ TAS2R31 ▸ RXFP4 ▸ GNAT3 ▸ PTGER3 ▸ LPAR5 ▸ CCR2 ▸
S1PR5 ▸ PMCH ▸ PPBP ▸ DARC ▸ SSTR5 ▸ HTR1E ▸ CCL25 ▸
GALR1 ▸ GRM8 ▸ HRH4 ▸ NMU ▸ OXER1 ▸ TAS2R41 ▸ GRM3 ▸
CCR1 ▸ P2RY13 ▸ GALR2 ▸ OPRD1 ▸ GABBR2 ▸ NMUR2 ▸ TAS2R45 ▸
CCR8 ▸ PYY ▸ GNAI3 ▸ DRD4 ▸ C3AR1 ▸ TAS2R43 ▸ PPY ▸
MTNR1A ▸ NPY2R ▸ SSTR2 ▸ FPR1 ▸ TAS2R42 ▸ GRM6 ▸ NPBWR2 ▸
TAS2R30 ▸ S1PR1 ▸ NMUR1 ▸ S1PR4 ▸ GALR3 ▸ TAS2R19 ▸ GRM7 ▸
HTR1F ▸ RXFP3 ▸ CCR9 ▸ ADRA2A ▸ TAS2R14 ▸ HTR5A ▸ CCL28 ▸
MTNR1B ▸ TAS2R9 ▸ P2RY4 ▸ HRH3 ▸ GRM2 ▸ PENK ▸ P2RY12 ▸
GRM4 ▸ NPY5R ▸ TAS2R60 ▸ BDKRB1 ▸ SSTR1 ▸ TAS2R10 ▸ XCR1 ▸
SUCNR1 ▸ TAS2R3 ▸ GABBR1 ▸ GNAI1 ▸ TAS2R7 ▸ CCR7 ▸ OPRL1 ▸
SSTR4 ▸ CHRM2 ▸ TAS2R20 ▸ TAS2R4 ▸ CHRM4 ▸ DRD2 ▸ KNG1 ▸
PNOC ▸ U2AF1 ▸ S1PR2 ▸ TAS2R40 ▸ ANXA1 ▸ TAS2R50 ▸ MCHR1 ▸
ADORA1 ▸ TAS2R1 ▸ CCL19 ▸ HTR1A ▸ TAS2R16 ▸ PTGDR2 ▸ PDYN ▸
TAS2R46 ▸ HTR1D ▸ TAS2R38 ▸ DRD3 ▸ CCR4 ▸ HTR1B ▸ TAS2R39 ▸
APLNR ▸ HCAR3 ▸ NPB ▸ OPRK1 ▸ FPR3 ▸ CCR6 ▸ GNB1 ▸
TAS2R13 ▸ INSL5 ▸ SSTR3 ▸ BDKRB2 ▸ TAS2R8 ▸ GNG2 ▸ ADRA2C ▸
NPBWR1 ▸ HCAR2 ▸ ADORA3 ▸ MT-RNR2 ▸ C5AR1 ▸ NPY1R ▸ S1PR3 ▸
Data information
Please see the Gene Interactions Track Manual.