Cell cycle (Georgetown, Tex.) 2006,
PMID: 16582619
Tompkins, Van; Hagen, Jussara; Zediak, Valerie P; Quelle, Dawn E
The ARF tumor suppressor protects us against cancer through protein-protein interactions in partially defined p53-dependent and p53-independent pathways. We performed a two-hybrid screen using ARF as bait and present the identification of several new ARF partners that may regulate its growth inhibitory signaling. The potential physiological roles of these novel ARF binding proteins in regulating ARF signaling are discussed.
Diseases/Pathways annotated by Medline MESH: Cell Transformation, Neoplastic
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Manually curated Databases
In total, 13 gene pairs are associated to this article in curated databases