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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining
EMBO J 2000, PMID: 11118221

The spliceosome deposits multiple proteins 20-24 nucleotides upstream of mRNA exon-exon junctions.

Le Hir, H; Izaurralde, E; Maquat, L E; Moore, M J

Eukaryotic mRNAs exist in vivo as ribonucleoprotein particles (mRNPs). The protein components of mRNPs have important functions in mRNA metabolism, including effects on subcellular localization, translational efficiency and mRNA half-life. There is accumulating evidence that pre-mRNA splicing can alter mRNP structure and thereby affect downstream mRNA metabolism. Here, we report that the spliceosome stably deposits several proteins on mRNAs, probably as a single complex of approximately 335 kDa. This complex protects 8 nucleotides of mRNA from complete RNase digestion at a conserved position 20-24 nucleotides upstream of exon-exon junctions. Splicing-dependent RNase protection of this region was observed in both HeLa cell nuclear extracts and Xenopus laevis oocyte nuclei. Immunoprecipitations revealed that five components of the complex are the splicing-associated factors SRm160, DEK and RNPS1, the mRNA-associated shuttling protein Y14 and the mRNA export factor REF. Possible functions for this complex in nucleocytoplasmic transport of spliced mRNA, as well as the nonsense-mediated mRNA decay pathway, are discussed.

Document information provided by NCBI PubMed

Text Mining Data

Dashed line = No text mining data

Manually curated Databases

  • IRef Bind Interaction: Complex of RBM8A-RNPS1-DEK-SRRM1
  • MIPS CORUM Splicing-associated factors complex: Splicing-associated factors complex complex (DEK-RBM8A-RNPS1-SRRM1-ALYREF)
  • IRef Corum Interaction: Complex of DEK-RNPS1-ALYREF-SRRM1-RBM8A (association, coimmunoprecipitation)
  • Reactome Reaction: MAGOH → SNRPG (indirect_complex)
  • Reactome Reaction: MAGOH → SRSF2 (indirect_complex)
  • Reactome Reaction: MAGOH → SF3B5 (reaction)
  • Reactome Reaction: U2AF1 → RBM8A (indirect_complex)
  • Reactome Reaction: SF3B4 → RBM8A (reaction)
  • Reactome Reaction: MAGOH → CD2BP2 (indirect_complex)
  • Reactome Reaction: MAGOH → CWC15 (indirect_complex)
  • Reactome Reaction: DNAJC8 → RBM8A (reaction)
  • Reactome Reaction: MAGOH → SNRPG (reaction)
  • Reactome Reaction: DHX38 → RBM8A (indirect_complex)
  • Reactome Reaction: RBM8A → CCAR1 (indirect_complex)
  • Reactome Reaction: MAGOH → PCBP2 (reaction)
  • Reactome Reaction: POLR2F → RBM8A (reaction)
  • Reactome Reaction: SNRPD1 → RBM8A (reaction)
  • Reactome Reaction: HSPA8 → RBM8A (reaction)
  • Reactome Reaction: MAGOH → BCAS2 (reaction)
  • Reactome Reaction: RBM8A → SNRNP40 (reaction)
  • Reactome Reaction: MAGOH → SNRPD1 (reaction)
  • Reactome Reaction: SMC1A → RBM8A (reaction)
  • Reactome Reaction: MAGOH → POLR2C (indirect_complex)
  • Reactome Reaction: NCBP1 → RBM8A (indirect_complex)
  • Reactome Reaction: SNRNP200 → RBM8A (indirect_complex)
  • Reactome Reaction: HSPA8 → RBM8A (indirect_complex)
  • Reactome Reaction: SRSF6 → RBM8A (indirect_complex)
  • Reactome Reaction: RBM8A → SRRM1 (indirect_complex)
  • Reactome Reaction: MAGOH → HNRNPUL1 (reaction)
  • Reactome Reaction: POLR2K → RBM8A (reaction)
  • Reactome Reaction: MAGOH → HNRNPH1 (reaction)
  • Reactome Reaction: RBM8A → PRPF19 (reaction)
  • Reactome Reaction: RBM8A → SUGP1 (indirect_complex)
  • Reactome Reaction: PAPOLA → RBM8A (indirect_complex)
  • Reactome Reaction: RBM8A → SUGP1 (reaction)
  • Reactome Reaction: MAGOH → DDX23 (indirect_complex)
  • Reactome Reaction: MAGOH → PCF11 (reaction)
  • Reactome Reaction: NCBP2 → RBM8A (reaction)
  • Reactome Reaction: PCF11 → RBM8A (indirect_complex)
  • Reactome Reaction: MAGOH → CTNNBL1 (indirect_complex)
  • Reactome Reaction: POLR2B → RBM8A (indirect_complex)
  • Reactome Reaction: GTF2F2 → RBM8A (reaction)
  • Reactome Reaction: HNRNPC → RBM8A (indirect_complex)
  • Reactome Reaction: MAGOH → SRRM1 (indirect_complex)
  • Reactome Reaction: SRSF4 → RBM8A (indirect_complex)
  • Reactome Reaction: HNRNPK → RBM8A (indirect_complex)
  • Reactome Reaction: HNRNPA2B1 → RBM8A (indirect_complex)
  • Reactome Reaction: MAGOH → CPSF7 (indirect_complex)
  • Reactome Reaction: MAGOH → SRSF3 (indirect_complex)
  • Reactome Reaction: CPSF1 → RBM8A (indirect_complex)
  • Reactome Reaction: MAGOH → HNRNPF (indirect_complex)
  • Reactome Reaction: MAGOH → SNRPD2 (indirect_complex)
  • Reactome Reaction: MAGOH → HNRNPA1 (indirect_complex)
  • Reactome Reaction: MAGOH → CPSF3 (indirect_complex)
  • Reactome Reaction: POLR2A → RBM8A (indirect_complex)
  • Reactome Reaction: SF3A2 → RBM8A (indirect_complex)
  • Reactome Reaction: U2AF2 → RBM8A (reaction)
  • Reactome Reaction: MAGOH → PTBP1 (reaction)
  • Reactome Reaction: EFTUD2 → RBM8A (reaction)
  • Reactome Reaction: PHF5A → RBM8A (reaction)
  • Reactome Reaction: RBM8A → CCAR1 (reaction)
  • Reactome Reaction: RBM8A → PRPF19 (indirect_complex)
  • Reactome Reaction: MAGOH → YBX1 (indirect_complex)
  • Reactome Reaction: HNRNPR → RBM8A (indirect_complex)
  • Reactome Reaction: MAGOH → SRSF3 (reaction)
  • Reactome Reaction: POLR2C → RBM8A (indirect_complex)
  • Reactome Reaction: MAGOH → POLR2F (indirect_complex)
  • Reactome Reaction: MAGOH → HNRNPA0 (reaction)
  • Reactome Reaction: MAGOH → HNRNPK (reaction)
  • Reactome Reaction: NCBP1 → MAGOH (indirect_complex)
  • Reactome Reaction: MAGOH → SF3B4 (indirect_complex)
  • Reactome Reaction: MAGOH → CD2BP2 (reaction)
  • Reactome Reaction: RBM8A → UPF3B (indirect_complex)
  • Reactome Reaction: MAGOH → POLR2C (reaction)
  • Reactome Reaction: CPSF3 → RBM8A (reaction)
  • Reactome Reaction: MAGOH → SNRNP200 (reaction)
  • Reactome Reaction: MAGOH → SMC1A (indirect_complex)
  • Reactome Reaction: RBM8A → RNPS1 (reaction)
  • Reactome Reaction: MAGOH → PAPOLA (reaction)
  • Reactome Reaction: SNRPA1 → RBM8A (indirect_complex)
  • Reactome Reaction: MAGOH → U2AF2 (indirect_complex)
  • Reactome Reaction: MAGOH → GTF2F1 (reaction)
  • Reactome Reaction: MAGOH → SNRNP200 (indirect_complex)
  • Reactome Reaction: EFTUD2 → RBM8A (indirect_complex)
  • Reactome Reaction: MAGOH → SRSF9 (reaction)
  • Reactome Reaction: MAGOH → HNRNPM (indirect_complex)
  • Reactome Reaction: CSTF1 → RBM8A (reaction)
  • Reactome Reaction: MAGOH → SRSF11 (reaction)
  • Reactome Reaction: MAGOH → SRSF11 (indirect_complex)
  • Reactome Reaction: MAGOH → CPSF3 (reaction)
  • Reactome Reaction: NCBP2 → RBM8A (indirect_complex)
  • Reactome Reaction: MAGOH → SRSF6 (indirect_complex)
  • Reactome Reaction: RBM5 → RBM8A (reaction)
  • Reactome Reaction: MAGOH → POLR2D (indirect_complex)
  • Reactome Reaction: MAGOH → DDX23 (reaction)
  • Reactome Reaction: MAGOH → CPSF1 (indirect_complex)
  • Reactome Reaction: RBM8A → HNRNPUL1 (indirect_complex)
  • Reactome Reaction: SRSF1 → RBM8A (indirect_complex)
  • Reactome Reaction: HSPA8 → MAGOH (reaction)
  • Reactome Reaction: DHX38 → RBM8A (reaction)
  • Reactome Reaction: MAGOH → PABPN1 (indirect_complex)
  • Reactome Reaction: MAGOH → SNRPA1 (indirect_complex)
  • Reactome Reaction: PRPF4 → RBM8A (indirect_complex)
  • Reactome Reaction: MAGOH → POLR2E (indirect_complex)
  • Reactome Reaction: MAGOH → SNRPF (indirect_complex)
  • Reactome Reaction: MAGOH → PRPF4 (indirect_complex)
  • Reactome Reaction: HNRNPF → RBM8A (reaction)
  • Reactome Reaction: SRSF2 → RBM8A (indirect_complex)
  • Reactome Reaction: MAGOH → SRSF5 (reaction)
  • Reactome Reaction: SNRPD2 → RBM8A (reaction)
  • Reactome Reaction: MAGOH → SUGP1 (indirect_complex)
  • Reactome Reaction: SRSF5 → RBM8A (reaction)
  • Reactome Reaction: SF3B1 → RBM8A (reaction)
  • Reactome Reaction: MAGOH → CWC15 (reaction)
  • Reactome Reaction: SNRPD3 → RBM8A (reaction)
  • Reactome Reaction: MAGOH → POLR2E (reaction)
  • Reactome Reaction: DDX23 → RBM8A (reaction)
  • Reactome Reaction: MAGOH → SRSF4 (indirect_complex)
  • Reactome Reaction: SNRNP200 → RBM8A (reaction)
  • Reactome Reaction: HNRNPH2 → RBM8A (reaction)
  • Reactome Reaction: MAGOH → PCF11 (indirect_complex)
  • Reactome Reaction: MAGOH → SNRPD3 (reaction)
  • Reactome Reaction: PABPN1 → RBM8A (reaction)
  • Reactome Reaction: POLR2E → RBM8A (indirect_complex)
  • Reactome Reaction: HNRNPD → RBM8A (reaction)
  • Reactome Reaction: RBM8A → PRPF8 (reaction)
  • Reactome Reaction: MAGOH → SF3A1 (indirect_complex)
  • Reactome Reaction: MAGOH → HNRNPA2B1 (indirect_complex)
  • Reactome Reaction: RBM8A → UPF3B (reaction)
  • Reactome Reaction: RBM8A → SRRM1 (reaction)
  • Reactome Reaction: MAGOH → NHP2L1 (reaction)
  • Reactome Reaction: MAGOH → SF3B5 (indirect_complex)
  • Reactome Reaction: MAGOH → SRSF9 (indirect_complex)
  • Reactome Reaction: MAGOH → HNRNPL (reaction)
  • Reactome Reaction: MAGOH → SF3A1 (reaction)
  • Reactome Reaction: SRSF3 → RBM8A (indirect_complex)
  • Reactome Reaction: MAGOH → SNRPD2 (reaction)
  • Reactome Reaction: SRSF7 → RBM8A (indirect_complex)
  • Reactome Reaction: MAGOH → PLRG1 (indirect_complex)
  • Reactome Reaction: PHF5A → RBM8A (indirect_complex)
  • Reactome Reaction: MAGOH → SRRM1 (reaction)
  • Reactome Reaction: NHP2L1 → RBM8A (indirect_complex)
  • Reactome Reaction: MAGOH → SNRPF (reaction)
  • Reactome Reaction: SNRPD1 → RBM8A (indirect_complex)
  • Reactome Reaction: MAGOH → POLR2I (reaction)
  • Reactome Reaction: MAGOH → GTF2F2 (reaction)
  • Reactome Reaction: MAGOH → RNPS1 (reaction)
  • Reactome Reaction: HNRNPA3 → RBM8A (indirect_complex)
  • Reactome Reaction: MAGOH → SF3A2 (indirect_complex)
  • Reactome Reaction: RBM8A → BCAS2 (reaction)
  • Reactome Reaction: PCBP1 → RBM8A (reaction)
  • Reactome Reaction: MAGOH → HNRNPA3 (indirect_complex)
  • Reactome Reaction: MAGOH → HNRNPC (indirect_complex)
  • Reactome Reaction: MAGOH → PRPF19 (reaction)
  • Reactome Reaction: HNRNPD → RBM8A (indirect_complex)
  • Reactome Reaction: MAGOH → SNRPE (indirect_complex)
  • Reactome Reaction: HNRNPU → RBM8A (indirect_complex)
  • Reactome Reaction: PCBP1 → RBM8A (indirect_complex)
  • Reactome Reaction: MAGOH → PABPN1 (reaction)
  • Reactome Reaction: MAGOH → POLR2A (indirect_complex)
  • Reactome Reaction: RBM8A → ALYREF (reaction)
  • Reactome Reaction: DHX9 → MAGOH (indirect_complex)
  • Reactome Reaction: DNAJC8 → MAGOH (reaction)
  • Reactome Reaction: POLR2C → RBM8A (reaction)
  • Reactome Reaction: MAGOH → POLR2H (reaction)
  • Reactome Reaction: MAGOH → GTF2F2 (indirect_complex)
  • Reactome Reaction: MAGOH → SRSF1 (indirect_complex)
  • Reactome Reaction: SNRPE → RBM8A (reaction)
  • Reactome Reaction: MAGOH → RNPS1 (indirect_complex)
  • Reactome Reaction: RBM8A → ALYREF (indirect_complex)
  • Reactome Reaction: CDC40 → RBM8A (indirect_complex)
  • Reactome Reaction: FUS → RBM8A (indirect_complex)
  • Reactome Reaction: SRSF9 → RBM8A (reaction)
  • Reactome Reaction: MAGOH → SNRPB (reaction)
  • Reactome Reaction: RBM8A → HNRNPUL1 (reaction)
  • Reactome Reaction: HNRNPA1 → RBM8A (indirect_complex)
  • Reactome Reaction: MAGOH → HNRNPA0 (indirect_complex)
  • Reactome Reaction: MAGOH → CSTF3 (reaction)
  • Reactome Reaction: SF3B4 → RBM8A (indirect_complex)
  • Reactome Reaction: RBM8A → PLRG1 (indirect_complex)
  • Reactome Reaction: MAGOH → SNRPB2 (indirect_complex)
  • Reactome Reaction: MAGOH → POLR2H (indirect_complex)
  • Reactome Reaction: MAGOH → CPSF7 (reaction)
  • Reactome Reaction: HNRNPU → RBM8A (reaction)
  • Reactome Reaction: PCBP2 → RBM8A (reaction)
  • Reactome Reaction: TXNL4A → RBM8A (indirect_complex)
  • Reactome Reaction: SNRPF → RBM8A (indirect_complex)
  • Reactome Reaction: MAGOH → HNRNPL (indirect_complex)
  • Reactome Reaction: MAGOH → SF3B1 (reaction)
  • Reactome Reaction: GTF2F2 → RBM8A (indirect_complex)
  • Reactome Reaction: MAGOH → CDC5L (indirect_complex)
  • Reactome Reaction: CPSF3 → RBM8A (indirect_complex)
  • Reactome Reaction: SNRPG → RBM8A (reaction)
  • Reactome Reaction: MAGOH → SNRNP40 (reaction)
  • Reactome Reaction: SRSF7 → RBM8A (reaction)
  • Reactome Reaction: PTBP1 → RBM8A (indirect_complex)
  • Reactome Reaction: HNRNPL → RBM8A (indirect_complex)
  • Reactome Reaction: MAGOH → PAPOLA (indirect_complex)
  • Reactome Reaction: SRSF1 → RBM8A (reaction)
  • Reactome Reaction: MAGOH → UPF3B (indirect_complex)
  • Reactome Reaction: MAGOH → UPF3B (reaction)
  • Reactome Reaction: MAGOH → LSM2 (indirect_complex)
  • Reactome Reaction: MAGOH → POLR2K (indirect_complex)
  • Reactome Reaction: HNRNPM → RBM8A (indirect_complex)
  • Reactome Reaction: SRSF11 → RBM8A (reaction)
  • Reactome Reaction: MAGOH → ALYREF (indirect_complex)
  • Reactome Reaction: PRPF6 → RBM8A (reaction)
  • Reactome Reaction: MAGOH → U2AF1 (indirect_complex)
  • Reactome Reaction: HNRNPA1 → RBM8A (reaction)
  • Reactome Reaction: POLR2B → RBM8A (reaction)
  • Reactome Reaction: SNRPB → RBM8A (indirect_complex)
  • Reactome Reaction: MAGOH → POLR2D (reaction)
  • Reactome Reaction: SF3B5 → RBM8A (reaction)
  • Reactome Reaction: MAGOH → SRSF1 (reaction)
  • Reactome Reaction: SRSF11 → RBM8A (indirect_complex)
  • Reactome Reaction: CPSF7 → RBM8A (indirect_complex)
  • Reactome Reaction: RBM8A → CSTF3 (indirect_complex)
  • Reactome Reaction: POLR2A → RBM8A (reaction)
  • Reactome Reaction: MAGOH → CSTF2 (reaction)
  • Reactome Reaction: MAGOH → CSTF3 (indirect_complex)
  • Reactome Reaction: LSM2 → RBM8A (reaction)
  • Reactome Reaction: MAGOH → LSM2 (reaction)
  • Reactome Reaction: GTF2F1 → RBM8A (reaction)
  • Reactome Reaction: MAGOH → TXNL4A (reaction)
  • Reactome Reaction: YBX1 → RBM8A (indirect_complex)
  • Reactome Reaction: SF3B3 → RBM8A (indirect_complex)
  • Reactome Reaction: SF3A2 → RBM8A (reaction)
  • Reactome Reaction: SF3A3 → RBM8A (reaction)
  • Reactome Reaction: MAGOH → CDC40 (indirect_complex)
  • Reactome Reaction: HNRNPM → RBM8A (reaction)
  • Reactome Reaction: SNRPF → RBM8A (reaction)
  • Reactome Reaction: CPSF2 → RBM8A (indirect_complex)
  • Reactome Reaction: MAGOH → PRPF8 (reaction)
  • Reactome Reaction: RBM8A → PLRG1 (reaction)
  • Reactome Reaction: POLR2E → RBM8A (reaction)
  • Reactome Reaction: MAGOH → SRSF7 (indirect_complex)
  • Reactome Reaction: CSTF1 → RBM8A (indirect_complex)
  • Reactome Reaction: CSTF2 → RBM8A (indirect_complex)
  • Reactome Reaction: MAGOH → NHP2L1 (indirect_complex)
  • Reactome Reaction: FUS → MAGOH (indirect_complex)
  • Reactome Reaction: MAGOH → NUDT21 (indirect_complex)
  • Reactome Reaction: HNRNPH1 → RBM8A (indirect_complex)
  • Reactome Reaction: PRPF4 → RBM8A (reaction)
  • Reactome Reaction: MAGOH → HNRNPD (reaction)
  • Reactome Reaction: MAGOH → CSTF1 (indirect_complex)
  • Reactome Reaction: SRSF9 → RBM8A (indirect_complex)
  • Reactome Reaction: PCF11 → RBM8A (reaction)
  • Reactome Reaction: TXNL4A → RBM8A (reaction)
  • Reactome Reaction: SNRPG → RBM8A (indirect_complex)
  • Reactome Reaction: MAGOH → PRPF6 (indirect_complex)
  • Reactome Reaction: RBM5 → RBM8A (indirect_complex)
  • Reactome Reaction: MAGOH → POLR2J (indirect_complex)
  • Reactome Reaction: MAGOH → HNRNPR (indirect_complex)
  • Reactome Reaction: MAGOH → PRPF8 (indirect_complex)
  • Reactome Reaction: MAGOH → HNRNPH1 (indirect_complex)
  • Reactome Reaction: MAGOH → SF3B4 (reaction)
  • Reactome Reaction: SNRPB2 → RBM8A (reaction)
  • Reactome Reaction: POLR2F → RBM8A (indirect_complex)
  • Reactome Reaction: MAGOH → PTBP1 (indirect_complex)
  • Reactome Reaction: DNAJC8 → MAGOH (indirect_complex)
  • Reactome Reaction: MAGOH → SF3B3 (reaction)
  • Reactome Reaction: RBM8A → PRPF8 (indirect_complex)
  • Reactome Reaction: MAGOH → POLR2A (reaction)
  • Reactome Reaction: HNRNPH1 → RBM8A (reaction)
  • Reactome Reaction: RBM8A → CSTF3 (reaction)
  • Reactome Reaction: MAGOH → ALYREF (reaction)
  • Reactome Reaction: MAGOH → RBMX (reaction)
  • Reactome Reaction: RBM8A → CWC15 (indirect_complex)
  • Reactome Reaction: MAGOH → SRSF2 (reaction)
  • Reactome Reaction: MAGOH → CPSF2 (indirect_complex)
  • Reactome Reaction: SMC1A → RBM8A (indirect_complex)
  • Reactome Reaction: MAGOH → SNRPB2 (reaction)
  • Reactome Reaction: MAGOH → SF3A2 (reaction)
  • Reactome Reaction: MAGOH → POLR2K (reaction)
  • Reactome Reaction: RBM8A → CDC5L (reaction)
  • Reactome Reaction: MAGOH → CCAR1 (reaction)
  • Reactome Reaction: FUS → RBM8A (reaction)
  • Reactome Reaction: MAGOH → POLR2B (indirect_complex)
  • Reactome Reaction: CDC40 → RBM8A (reaction)
  • Reactome Reaction: MAGOH → PHF5A (reaction)
  • Reactome Reaction: SNRPB2 → RBM8A (indirect_complex)
  • Reactome Reaction: YBX1 → RBM8A (reaction)
  • Reactome Reaction: MAGOH → POLR2B (reaction)
  • Reactome Reaction: GTF2F1 → RBM8A (indirect_complex)
  • Reactome Reaction: NHP2L1 → RBM8A (reaction)
  • Reactome Reaction: POLR2L → RBM8A (indirect_complex)
  • Reactome Reaction: LSM2 → RBM8A (indirect_complex)
  • Reactome Reaction: MAGOH → PLRG1 (reaction)
  • Reactome Reaction: HNRNPL → RBM8A (reaction)
  • Reactome Reaction: DHX9 → RBM8A (reaction)
  • Reactome Reaction: MAGOH → U2AF2 (reaction)
  • Reactome Reaction: SNRPA1 → RBM8A (reaction)
  • Reactome Reaction: MAGOH → POLR2L (reaction)
  • Reactome Reaction: RBMX → RBM8A (reaction)
  • Reactome Reaction: POLR2K → RBM8A (indirect_complex)
  • Reactome Reaction: PABPN1 → RBM8A (indirect_complex)
  • Reactome Reaction: MAGOH → DHX38 (indirect_complex)
  • Reactome Reaction: MAGOH → SUGP1 (reaction)
  • Reactome Reaction: MAGOH → PCBP1 (indirect_complex)
  • Reactome Reaction: MAGOH → YBX1 (reaction)
  • Reactome Reaction: MAGOH → HNRNPA2B1 (reaction)
  • Reactome Reaction: MAGOH → POLR2L (indirect_complex)
  • Reactome Reaction: FUS → MAGOH (reaction)
  • Reactome Reaction: MAGOH → HNRNPC (reaction)
  • Reactome Reaction: MAGOH → CPSF2 (reaction)
  • Reactome Reaction: PAPOLA → RBM8A (reaction)
  • Reactome Reaction: POLR2J → RBM8A (indirect_complex)
  • Reactome Reaction: CD2BP2 → RBM8A (reaction)
  • Reactome Reaction: NUDT21 → RBM8A (reaction)
  • Reactome Reaction: MAGOH → CLP1 (indirect_complex)
  • Reactome Reaction: MAGOH → HNRNPR (reaction)
  • Reactome Reaction: MAGOH → PHF5A (indirect_complex)
  • Reactome Reaction: POLR2G → RBM8A (reaction)
  • Reactome Reaction: MAGOH → SMC1A (reaction)
  • Reactome Reaction: MAGOH → SF3A3 (indirect_complex)
  • Reactome Reaction: POLR2D → RBM8A (reaction)
  • Reactome Reaction: POLR2D → RBM8A (indirect_complex)
  • Reactome Reaction: HNRNPA2B1 → RBM8A (reaction)
  • Reactome Reaction: SF3A3 → RBM8A (indirect_complex)
  • Reactome Reaction: HNRNPC → RBM8A (reaction)
  • Reactome Reaction: U2AF1 → RBM8A (reaction)
  • Reactome Reaction: CPSF2 → RBM8A (reaction)
  • Reactome Reaction: HNRNPA0 → RBM8A (reaction)
  • Reactome Reaction: SF3B2 → RBM8A (indirect_complex)
  • Reactome Reaction: CPSF7 → RBM8A (reaction)
  • Reactome Reaction: CD2BP2 → RBM8A (indirect_complex)
  • Reactome Reaction: POLR2J → RBM8A (reaction)
  • Reactome Reaction: MAGOH → SNRPD3 (indirect_complex)
  • Reactome Reaction: MAGOH → EFTUD2 (indirect_complex)
  • Reactome Reaction: U2AF2 → RBM8A (indirect_complex)
  • Reactome Reaction: MAGOH → HNRNPU (reaction)
  • Reactome Reaction: SRSF6 → RBM8A (reaction)
  • Reactome Reaction: SF3B3 → RBM8A (reaction)
  • Reactome Reaction: MAGOH → POLR2G (indirect_complex)
  • Reactome Reaction: MAGOH → NUDT21 (reaction)
  • Reactome Reaction: MAGOH → CLP1 (reaction)
  • Reactome Reaction: MAGOH → HNRNPH2 (indirect_complex)
  • Reactome Reaction: MAGOH → SNRPE (reaction)
  • Reactome Reaction: PTBP1 → RBM8A (reaction)
  • Reactome Reaction: POLR2G → RBM8A (indirect_complex)
  • Reactome Reaction: MAGOH → BCAS2 (indirect_complex)
  • Reactome Reaction: MAGOH → RBM5 (indirect_complex)
  • Reactome Reaction: SRSF2 → RBM8A (reaction)
  • Reactome Reaction: DDX23 → RBM8A (indirect_complex)
  • Reactome Reaction: CLP1 → RBM8A (reaction)
  • Reactome Reaction: POLR2H → RBM8A (reaction)
  • Reactome Reaction: MAGOH → U2AF1 (reaction)
  • Reactome Reaction: CTNNBL1 → RBM8A (indirect_complex)
  • Reactome Reaction: SF3B1 → RBM8A (indirect_complex)
  • Reactome Reaction: NCBP2 → MAGOH (reaction)
  • Reactome Reaction: MAGOH → PRPF4 (reaction)
  • Reactome Reaction: DHX9 → RBM8A (indirect_complex)
  • Reactome Reaction: MAGOH → SNRNP40 (indirect_complex)
  • Reactome Reaction: NUDT21 → RBM8A (indirect_complex)
  • Reactome Reaction: MAGOH → RBMX (indirect_complex)
  • Reactome Reaction: DHX9 → MAGOH (reaction)
  • Reactome Reaction: MAGOH → PCBP1 (reaction)
  • Reactome Reaction: NCBP1 → MAGOH (reaction)
  • Reactome Reaction: CPSF1 → RBM8A (reaction)
  • Reactome Reaction: RBM8A → BCAS2 (indirect_complex)
  • Reactome Reaction: MAGOH → HNRNPA1 (reaction)
  • Reactome Reaction: MAGOH → HNRNPH2 (reaction)
  • Reactome Reaction: HNRNPK → RBM8A (reaction)
  • Reactome Reaction: SRSF4 → RBM8A (reaction)
  • Reactome Reaction: MAGOH → SRSF4 (reaction)
  • Reactome Reaction: RBM8A → CWC15 (reaction)
  • Reactome Reaction: MAGOH → TXNL4A (indirect_complex)
  • Reactome Reaction: MAGOH → POLR2G (reaction)
  • Reactome Reaction: MAGOH → SF3B1 (indirect_complex)
  • Reactome Reaction: PCBP2 → RBM8A (indirect_complex)
  • Reactome Reaction: MAGOH → SF3B2 (reaction)
  • Reactome Reaction: MAGOH → RBM5 (reaction)
  • Reactome Reaction: MAGOH → SRSF6 (reaction)
  • Reactome Reaction: SRSF3 → RBM8A (reaction)
  • Reactome Reaction: NCBP2 → MAGOH (indirect_complex)
  • Reactome Reaction: NCBP1 → RBM8A (reaction)
  • Reactome Reaction: MAGOH → SNRPD1 (indirect_complex)
  • Reactome Reaction: MAGOH → HNRNPUL1 (indirect_complex)
  • Reactome Reaction: SNRPD3 → RBM8A (indirect_complex)
  • Reactome Reaction: SNRPB → RBM8A (reaction)
  • Reactome Reaction: HNRNPA0 → RBM8A (indirect_complex)
  • Reactome Reaction: SNRPD2 → RBM8A (indirect_complex)
  • Reactome Reaction: MAGOH → POLR2F (reaction)
  • Reactome Reaction: RBMX → RBM8A (indirect_complex)
  • Reactome Reaction: POLR2I → RBM8A (reaction)
  • Reactome Reaction: MAGOH → PRPF6 (reaction)
  • Reactome Reaction: MAGOH → SRSF7 (reaction)
  • Reactome Reaction: MAGOH → HNRNPA3 (reaction)
  • Reactome Reaction: MAGOH → HNRNPF (reaction)
  • Reactome Reaction: MAGOH → CSTF2 (indirect_complex)
  • Reactome Reaction: MAGOH → SF3B2 (indirect_complex)
  • Reactome Reaction: SF3B5 → RBM8A (indirect_complex)
  • Reactome Reaction: MAGOH → EFTUD2 (reaction)
  • Reactome Reaction: RBM8A → CDC5L (indirect_complex)
  • Reactome Reaction: MAGOH → SNRPA1 (reaction)
  • Reactome Reaction: MAGOH → GTF2F1 (indirect_complex)
  • Reactome Reaction: MAGOH → SRSF5 (indirect_complex)
  • Reactome Reaction: MAGOH → HNRNPM (reaction)
  • Reactome Reaction: HSPA8 → MAGOH (indirect_complex)
  • Reactome Reaction: SRSF5 → RBM8A (indirect_complex)
  • Reactome Reaction: RBM8A → RNPS1 (indirect_complex)
  • Reactome Reaction: MAGOH → CCAR1 (indirect_complex)
  • Reactome Reaction: MAGOH → CSTF1 (reaction)
  • Reactome Reaction: CSTF2 → RBM8A (reaction)
  • Reactome Reaction: HNRNPR → RBM8A (reaction)
  • Reactome Reaction: SF3A1 → RBM8A (indirect_complex)
  • Reactome Reaction: CTNNBL1 → RBM8A (reaction)
  • Reactome Reaction: MAGOH → POLR2I (indirect_complex)
  • Reactome Reaction: DNAJC8 → RBM8A (indirect_complex)
  • Reactome Reaction: POLR2I → RBM8A (indirect_complex)
  • Reactome Reaction: SF3B2 → RBM8A (reaction)
  • Reactome Reaction: CLP1 → RBM8A (indirect_complex)
  • Reactome Reaction: MAGOH → CDC5L (reaction)
  • Reactome Reaction: MAGOH → HNRNPK (indirect_complex)
  • Reactome Reaction: RBM8A → SNRNP40 (indirect_complex)
  • Reactome Reaction: MAGOH → DHX38 (reaction)
  • Reactome Reaction: SF3A1 → RBM8A (reaction)
  • Reactome Reaction: MAGOH → PRPF19 (indirect_complex)
  • Reactome Reaction: SNRPE → RBM8A (indirect_complex)
  • Reactome Reaction: MAGOH → SF3A3 (reaction)
  • Reactome Reaction: HNRNPF → RBM8A (indirect_complex)
  • Reactome Reaction: MAGOH → POLR2J (reaction)
  • Reactome Reaction: HNRNPA3 → RBM8A (reaction)
  • Reactome Reaction: POLR2L → RBM8A (reaction)
  • Reactome Reaction: HNRNPH2 → RBM8A (indirect_complex)
  • Reactome Reaction: MAGOH → SNRPB (indirect_complex)
  • Reactome Reaction: POLR2H → RBM8A (indirect_complex)
  • Reactome Reaction: MAGOH → CTNNBL1 (reaction)
  • Reactome Reaction: MAGOH → SF3B3 (indirect_complex)
  • Reactome Reaction: MAGOH → CPSF1 (reaction)
  • Reactome Reaction: MAGOH → PCBP2 (indirect_complex)
  • Reactome Reaction: MAGOH → HNRNPU (indirect_complex)
  • Reactome Reaction: PRPF6 → RBM8A (indirect_complex)
  • Reactome Reaction: MAGOH → HNRNPD (indirect_complex)
  • Reactome Reaction: MAGOH → CDC40 (reaction)
In total, 223 gene pairs are associated to this article in curated databases