Human Gene ZNF625 (ENST00000414892.5_6) from GENCODE V47lift37
  Description: zinc finger protein 625 (from HGNC ZNF625)
Gencode Transcript: ENST00000414892.5_6
Gencode Gene: ENSG00000257591.6_10
Transcript (Including UTRs)
   Position: hg19 chr19:12,252,905-12,258,617 Size: 5,713 Total Exon Count: 4 Strand: -
Coding Region
   Position: hg19 chr19:12,253,285-12,258,617 Size: 5,333 Coding Exon Count: 4 

Page IndexSequence and LinksUniProtKB CommentsPrimersCTDGene Alleles
RNA-Seq ExpressionRNA StructureProtein StructureOther SpeciesGO AnnotationsmRNA Descriptions
Other NamesModel InformationMethods
Data last updated at UCSC: 2024-08-22 23:36:26

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr19:12,252,905-12,258,617)mRNA (may differ from genome)Protein (104 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaAlphaFold
BioGPSEnsemblExonPrimerGeneCardsHGNCMGI
PubMedUniProtKB

-  Comments and Description Text from UniProtKB
  ID: H7C2C9_HUMAN
DESCRIPTION: SubName: Full=Zinc finger protein 625; Flags: Fragment;
CAUTION: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 6.72 RPKM in Pituitary
Total median expression: 152.90 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
3' UTR -57.40380-0.151 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR001909 - Krueppel-associated_box

Pfam Domains:
PF01352 - KRAB box

SCOP Domains:
47095 - HMG-box
109640 - KRAB domain (Kruppel-associated box)

ModBase Predicted Comparative 3D Structure on H7C2C9
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
      
      
      
      
      

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0003676 nucleic acid binding

Biological Process:
GO:0006355 regulation of transcription, DNA-templated

Cellular Component:
GO:0005622 intracellular


-  Descriptions from all associated GenBank mRNAs
  AK096560 - Homo sapiens cDNA FLJ39241 fis, clone OCBBF2008116, moderately similar to ZINC FINGER PROTEIN ZFP-36.
AK292455 - Homo sapiens cDNA FLJ77606 complete cds, highly similar to Homo sapiens zinc finger protein 625 (ZNF625), mRNA.
AX721266 - Sequence 226 from Patent WO0220754.
BC007868 - Homo sapiens zinc finger protein 625, mRNA (cDNA clone MGC:14429 IMAGE:4303049), complete cds.
BC143563 - Homo sapiens zinc finger protein 625, mRNA (cDNA clone MGC:177091 IMAGE:9052074), complete cds.
BC101591 - Homo sapiens zinc finger protein 625, mRNA (cDNA clone MGC:126640 IMAGE:8069097), complete cds.
BC101589 - Homo sapiens zinc finger protein 625, mRNA (cDNA clone MGC:126638 IMAGE:8069095), complete cds.
JD304914 - Sequence 285938 from Patent EP1572962.
JD530206 - Sequence 511230 from Patent EP1572962.
JD267882 - Sequence 248906 from Patent EP1572962.
JD103813 - Sequence 84837 from Patent EP1572962.
JD504871 - Sequence 485895 from Patent EP1572962.
JD365462 - Sequence 346486 from Patent EP1572962.
JD326367 - Sequence 307391 from Patent EP1572962.
JD546086 - Sequence 527110 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: AK096560, ENST00000414892.1, ENST00000414892.2, ENST00000414892.3, ENST00000414892.4, H7C2C9, H7C2C9_HUMAN, uc319ksp.1, ZNF625
UCSC ID: ENST00000414892.5_6
RefSeq Accession: NR_037802.1
Protein: H7C2C9

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.