Human Gene ZMYM1 (ENST00000359858.9_4) from GENCODE V47lift37

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Description: zinc finger MYM-type containing 1, transcript variant 5 (from RefSeq NM_024772.5)
Gencode Transcript: ENST00000359858.9_4
Gencode Gene: ENSG00000197056.12_11
Transcript (Including UTRs)
Position: hg19 chr1:35,544,986-35,581,460 Size: 36,475 Total Exon Count: 10 Strand: +
Coding Region
Position: hg19 chr1:35,559,589-35,580,860 Size: 21,272 Coding Exon Count: 9

Page Index	Sequence and Links	UniProtKB Comments	Primers	CTD	Gene Alleles
RNA-Seq Expression	RNA Structure	Protein Structure	Other Species	GO Annotations	mRNA Descriptions
Other Names	Model Information	Methods

Data last updated at UCSC: 2024-08-22 23:36:26

Sequence and Links to Tools and Databases

Genomic Sequence (chr1:35,544,986-35,581,460)			mRNA (may differ from genome)		Protein (1142 aa)
Gene Sorter	Genome Browser	Other Species FASTA	VisiGene	Gene interactions	Table Schema
AlphaFold	BioGPS	Ensembl	Entrez Gene	ExonPrimer	GeneCards
HGNC	MGI	PubMed	UniProtKB	Wikipedia	BioGrid CRISPR DB

Comments and Description Text from UniProtKB


	ID: ZMYM1_HUMAN DESCRIPTION: RecName: Full=Zinc finger MYM-type protein 1; SUBCELLULAR LOCATION: Nucleus (Potential). SIMILARITY: Contains 4 MYM-type zinc fingers. SIMILARITY: Contains 1 TTF-type zinc finger.

Primer design for this transcript

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3

Comparative Toxicogenomics Database (CTD)


	The following chemicals interact with this gene D000082 Acetaminophen C016403 2,4-dinitrotoluene C009505 4,4'-diaminodiphenylmethane D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide D000535 Aluminum D019327 Copper Sulfate D018817 N-Methyl-3,4-methylenedioxyamphetamine D010269 Paraquat D012402 Rotenone C004648 testosterone enanthate

Common Gene Haplotype Alleles


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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)


	Highest median expression: 4.61 RPKM in Testis Total median expression: 102.01 RPKM View in GTEx track of Genome Browser View at GTEx portal View GTEx Body Map

mRNA Secondary Structure of 3' and 5' UTRs

Region	Fold Energy	Bases	Energy/Base	Display As
5' UTR	-34.00	132	-0.258	Picture	PostScript	Text
3' UTR	-116.30	600	-0.194	Picture	PostScript	Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

Protein Domain and Structure Information

InterPro Domains: Graphical view of domain structure
IPR025398 - DUF4371
IPR008906 - HATC
IPR012337 - RNaseH-like_dom
IPR011017 - TRASH
IPR010507 - Znf_MYM
IPR006580 - Znf_TTF

Pfam Domains:
PF05699 - hAT family C-terminal dimerisation region
PF06467 - MYM-type Zinc finger with FCS sequence motif
PF14291 - Domain of unknown function (DUF4371)

SCOP Domains:
53098 - Ribonuclease H-like
57716 - Glucocorticoid receptor-like (DNA-binding domain)

ModBase Predicted Comparative 3D Structure on Q5SVZ6


Front	Top	Side

The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

Orthologous Genes in Other Species

Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.

Mouse	Rat	Zebrafish	D. melanogaster	C. elegans	S. cerevisiae
No ortholog	No ortholog	No ortholog	No ortholog	No ortholog	No ortholog
Gene Details	Gene Details
Gene Sorter	Gene Sorter
	RGD

Gene Ontology (GO) Annotations with Structured Vocabulary


	Molecular Function: GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding GO:0003677 DNA binding GO:0008270 zinc ion binding GO:0046872 metal ion binding GO:0046983 protein dimerization activity Biological Process: GO:0006357 regulation of transcription from RNA polymerase II promoter Cellular Component: GO:0005634 nucleus GO:0005654 nucleoplasm GO:0005737 cytoplasm

Descriptions from all associated GenBank mRNAs


	LF206622 - JP 2014500723-A/14125: Polycomb-Associated Non-Coding RNAs. MA442199 - JP 2018138019-A/14125: Polycomb-Associated Non-Coding RNAs. AK125741 - Homo sapiens cDNA FLJ43753 fis, clone TESTI2040018, highly similar to Zinc finger MYM-type protein 1. AK299779 - Homo sapiens cDNA FLJ57000 complete cds, highly similar to Zinc finger MYM-type protein 1. LF383909 - JP 2014500723-A/191412: Polycomb-Associated Non-Coding RNAs. CR936813 - Homo sapiens mRNA; cDNA DKFZp686B02126 (from clone DKFZp686B02126). AK308655 - Homo sapiens cDNA, FLJ98696. AK096206 - Homo sapiens cDNA FLJ38887 fis, clone MESAN2018670. BC037313 - Homo sapiens zinc finger, MYM-type 1, mRNA (cDNA clone IMAGE:5260856), containing frame-shift errors. BX648307 - Homo sapiens mRNA; cDNA DKFZp686H19119 (from clone DKFZp686H19119). BX537537 - Homo sapiens mRNA; cDNA DKFZp313O1925 (from clone DKFZp313O1925). KJ903233 - Synthetic construct Homo sapiens clone ccsbBroadEn_12627 ZMYM1 gene, encodes complete protein. LF356665 - JP 2014500723-A/164168: Polycomb-Associated Non-Coding RNAs. LF356664 - JP 2014500723-A/164167: Polycomb-Associated Non-Coding RNAs. LF356663 - JP 2014500723-A/164166: Polycomb-Associated Non-Coding RNAs. LF356662 - JP 2014500723-A/164165: Polycomb-Associated Non-Coding RNAs. LF356661 - JP 2014500723-A/164164: Polycomb-Associated Non-Coding RNAs. LF356660 - JP 2014500723-A/164163: Polycomb-Associated Non-Coding RNAs. AK026804 - Homo sapiens cDNA: FLJ23151 fis, clone LNG09417. LF356659 - JP 2014500723-A/164162: Polycomb-Associated Non-Coding RNAs. LF356658 - JP 2014500723-A/164161: Polycomb-Associated Non-Coding RNAs. LF356657 - JP 2014500723-A/164160: Polycomb-Associated Non-Coding RNAs. JD433638 - Sequence 414662 from Patent EP1572962. LF356656 - JP 2014500723-A/164159: Polycomb-Associated Non-Coding RNAs. LF356655 - JP 2014500723-A/164158: Polycomb-Associated Non-Coding RNAs. JD552961 - Sequence 533985 from Patent EP1572962. JD265721 - Sequence 246745 from Patent EP1572962. JD298159 - Sequence 279183 from Patent EP1572962. JD143636 - Sequence 124660 from Patent EP1572962. LF356654 - JP 2014500723-A/164157: Polycomb-Associated Non-Coding RNAs. JD250654 - Sequence 231678 from Patent EP1572962. JD327344 - Sequence 308368 from Patent EP1572962. JD530597 - Sequence 511621 from Patent EP1572962. JD307990 - Sequence 289014 from Patent EP1572962. JD225971 - Sequence 206995 from Patent EP1572962. JD566621 - Sequence 547645 from Patent EP1572962. JD538814 - Sequence 519838 from Patent EP1572962. MA619486 - JP 2018138019-A/191412: Polycomb-Associated Non-Coding RNAs. MA592242 - JP 2018138019-A/164168: Polycomb-Associated Non-Coding RNAs. MA592241 - JP 2018138019-A/164167: Polycomb-Associated Non-Coding RNAs. MA592240 - JP 2018138019-A/164166: Polycomb-Associated Non-Coding RNAs. MA592239 - JP 2018138019-A/164165: Polycomb-Associated Non-Coding RNAs. MA592238 - JP 2018138019-A/164164: Polycomb-Associated Non-Coding RNAs. MA592237 - JP 2018138019-A/164163: Polycomb-Associated Non-Coding RNAs. MA592236 - JP 2018138019-A/164162: Polycomb-Associated Non-Coding RNAs. MA592235 - JP 2018138019-A/164161: Polycomb-Associated Non-Coding RNAs. MA592234 - JP 2018138019-A/164160: Polycomb-Associated Non-Coding RNAs. MA592233 - JP 2018138019-A/164159: Polycomb-Associated Non-Coding RNAs. MA592232 - JP 2018138019-A/164158: Polycomb-Associated Non-Coding RNAs. MA592231 - JP 2018138019-A/164157: Polycomb-Associated Non-Coding RNAs.

Other Names for This Gene


	Alternate Gene Symbols: D3DPR7, ENST00000359858.1, ENST00000359858.2, ENST00000359858.3, ENST00000359858.4, ENST00000359858.5, ENST00000359858.6, ENST00000359858.7, ENST00000359858.8, NM_024772, Q5SVZ6, Q7Z3Q4, uc318bgf.1, uc318bgf.2, ZMYM1_HUMAN UCSC ID: ENST00000359858.9_4 RefSeq Accession: NM_024772.5 Protein: Q5SVZ6 (aka ZMYM1_HUMAN)

Gene Model Information


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Methods, Credits, and Use Restrictions


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