Human Gene WDR36 (ENST00000513710.4_7) from GENCODE V47lift37

JavaScript is disabled in your web browser

You must have JavaScript enabled in your web browser to use the Genome Browser

Description: WD repeat domain 36 (from RefSeq NM_139281.3)
Gencode Transcript: ENST00000513710.4_7
Gencode Gene: ENSG00000134987.13_11
Transcript (Including UTRs)
Position: hg19 chr5:110,428,046-110,466,200 Size: 38,155 Total Exon Count: 23 Strand: +
Coding Region
Position: hg19 chr5:110,428,155-110,462,581 Size: 34,427 Coding Exon Count: 23

Page Index	Sequence and Links	Primers	MalaCards	CTD	Gene Alleles
RNA-Seq Expression	Microarray Expression	RNA Structure	Other Species	mRNA Descriptions	Other Names
Model Information	Methods

Data last updated at UCSC: 2024-08-22 23:36:26

Sequence and Links to Tools and Databases

Genomic Sequence (chr5:110,428,046-110,466,200)			mRNA (may differ from genome)		Protein (895 aa)
Gene Sorter	Genome Browser	Other Species FASTA	VisiGene	Gene interactions	Table Schema
AlphaFold	BioGPS	Ensembl	Entrez Gene	ExonPrimer	GeneCards
HGNC	Malacards	MGI	OMIM	PubMed	UniProtKB
Wikipedia	BioGrid CRISPR DB

Primer design for this transcript

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3

MalaCards Disease Associations


	MalaCards Gene Search: WDR36 Diseases sorted by gene-association score: glaucoma 1, open angle, g* (1242), glaucoma 1, open angle, e* (59), open-angle glaucoma (34), preimplantation embryonic lethality (10), primary congenital glaucoma (10), glaucoma, normal tension (6), lagophthalmos (6), juvenile glaucoma (6), adamantinoma of long bones (1) * = Manually curated disease association

Comparative Toxicogenomics Database (CTD)


	The following chemicals interact with this gene D000082 Acetaminophen C006780 bisphenol A C016403 2,4-dinitrotoluene C023514 2,6-dinitrotoluene C009505 4,4'-diaminodiphenylmethane C035207 4-amino-2,6-dinitrotoluene D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide D001564 Benzo(a)pyrene D002117 Calcitriol D002251 Carbon Tetrachloride more ... click here to view the complete list

Common Gene Haplotype Alleles


	Press "+" in the title bar above to open this section.

RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)


	Highest median expression: 11.77 RPKM in Cells - EBV-transformed lymphocytes Total median expression: 202.20 RPKM View in GTEx track of Genome Browser View at GTEx portal View GTEx Body Map

Microarray Expression Data


	Press "+" in the title bar above to open this section.

mRNA Secondary Structure of 3' and 5' UTRs

Region	Fold Energy	Bases	Energy/Base	Display As
5' UTR	-36.20	109	-0.332	Picture	PostScript	Text
3' UTR	-835.60	3619	-0.231	Picture	PostScript	Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

Orthologous Genes in Other Species

Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.

Mouse	Rat	Zebrafish	D. melanogaster	C. elegans	S. cerevisiae
No ortholog	No ortholog	No ortholog	No ortholog	Genome Browser	Genome Browser
Gene Details	Gene Details		Gene Details	Gene Details	Gene Details
Gene Sorter	Gene Sorter		Gene Sorter	Gene Sorter	Gene Sorter
	RGD	Ensembl		WormBase	SGD
				Protein Sequence	Protein Sequence
				Alignment	Alignment

Descriptions from all associated GenBank mRNAs


	AF385437 - Homo sapiens T-cell activation WD repeat protein mRNA, complete cds. BC133025 - Homo sapiens WD repeat domain 36, mRNA (cDNA clone MGC:164656 IMAGE:40147047), complete cds. BC136517 - Homo sapiens WD repeat domain 36, mRNA (cDNA clone MGC:168130 IMAGE:9020507), complete cds. LF210999 - JP 2014500723-A/18502: Polycomb-Associated Non-Coding RNAs. KJ900161 - Synthetic construct Homo sapiens clone ccsbBroadEn_09555 WDR36 gene, encodes complete protein. KR712002 - Synthetic construct Homo sapiens clone CCSBHm_00034606 WDR36 (WDR36) mRNA, encodes complete protein. KR712003 - Synthetic construct Homo sapiens clone CCSBHm_00034608 WDR36 (WDR36) mRNA, encodes complete protein. KR712004 - Synthetic construct Homo sapiens clone CCSBHm_00034613 WDR36 (WDR36) mRNA, encodes complete protein. KR712005 - Synthetic construct Homo sapiens clone CCSBHm_00034621 WDR36 (WDR36) mRNA, encodes complete protein. AK095312 - Homo sapiens cDNA FLJ37993 fis, clone CTONG2011815. AL832494 - Homo sapiens mRNA; cDNA DKFZp686A0851 (from clone DKFZp686A0851). LF342960 - JP 2014500723-A/150463: Polycomb-Associated Non-Coding RNAs. LF342963 - JP 2014500723-A/150466: Polycomb-Associated Non-Coding RNAs. LF342966 - JP 2014500723-A/150469: Polycomb-Associated Non-Coding RNAs. CR749211 - Homo sapiens mRNA; cDNA DKFZp686I1650 (from clone DKFZp686I1650). AK074202 - Homo sapiens cDNA FLJ23622 fis, clone ADSE01512. LF342967 - JP 2014500723-A/150470: Polycomb-Associated Non-Coding RNAs. LF342969 - JP 2014500723-A/150472: Polycomb-Associated Non-Coding RNAs. BC037427 - Homo sapiens WD repeat domain 36, mRNA (cDNA clone IMAGE:5533588), with apparent retained intron. LF342971 - JP 2014500723-A/150474: Polycomb-Associated Non-Coding RNAs. LF342974 - JP 2014500723-A/150477: Polycomb-Associated Non-Coding RNAs. LF342975 - JP 2014500723-A/150478: Polycomb-Associated Non-Coding RNAs. LF342976 - JP 2014500723-A/150479: Polycomb-Associated Non-Coding RNAs. LF342977 - JP 2014500723-A/150480: Polycomb-Associated Non-Coding RNAs. LF342978 - JP 2014500723-A/150481: Polycomb-Associated Non-Coding RNAs. LF342979 - JP 2014500723-A/150482: Polycomb-Associated Non-Coding RNAs. AK055664 - Homo sapiens cDNA FLJ31102 fis, clone IMR322000010. MA578537 - JP 2018138019-A/150463: Polycomb-Associated Non-Coding RNAs. MA578540 - JP 2018138019-A/150466: Polycomb-Associated Non-Coding RNAs. MA578543 - JP 2018138019-A/150469: Polycomb-Associated Non-Coding RNAs. MA578544 - JP 2018138019-A/150470: Polycomb-Associated Non-Coding RNAs. MA578546 - JP 2018138019-A/150472: Polycomb-Associated Non-Coding RNAs. MA578548 - JP 2018138019-A/150474: Polycomb-Associated Non-Coding RNAs. MA578551 - JP 2018138019-A/150477: Polycomb-Associated Non-Coding RNAs. MA578552 - JP 2018138019-A/150478: Polycomb-Associated Non-Coding RNAs. MA578553 - JP 2018138019-A/150479: Polycomb-Associated Non-Coding RNAs. MA578554 - JP 2018138019-A/150480: Polycomb-Associated Non-Coding RNAs. MA578555 - JP 2018138019-A/150481: Polycomb-Associated Non-Coding RNAs. MA578556 - JP 2018138019-A/150482: Polycomb-Associated Non-Coding RNAs. MA446576 - JP 2018138019-A/18502: Polycomb-Associated Non-Coding RNAs.

Other Names for This Gene


	Alternate Gene Symbols: A0A0A0MTB8, A0A0A0MTB8_HUMAN, ENST00000513710.1, ENST00000513710.2, ENST00000513710.3, NM_139281, uc323koa.1, uc323koa.2, WDR36 UCSC ID: ENST00000513710.4_7 RefSeq Accession: NM_139281.3

Gene Model Information


	Click here for a detailed description of the fields of the table above.

Methods, Credits, and Use Restrictions


	Click here for details on how this gene model was made and data restrictions if any.