ID:UBP49_HUMAN DESCRIPTION: RecName: Full=Ubiquitin carboxyl-terminal hydrolase 49; EC=3.4.19.12; AltName: Full=Deubiquitinating enzyme 49; AltName: Full=Ubiquitin thioesterase 49; AltName: Full=Ubiquitin-specific-processing protease 49; CATALYTIC ACTIVITY: Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C- terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal). SIMILARITY: Belongs to the peptidase C19 family. SIMILARITY: Contains 1 UBP-type zinc finger.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Pfam Domains: PF00443 - Ubiquitin carboxyl-terminal hydrolase PF02148 - Zn-finger in ubiquitin-hydrolases and other protein PF13423 - Ubiquitin carboxyl-terminal hydrolase
ModBase Predicted Comparative 3D Structure on Q70CQ1
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.