ID:TRI29_HUMAN DESCRIPTION: RecName: Full=Tripartite motif-containing protein 29; AltName: Full=Ataxia telangiectasia group D-associated protein; FUNCTION: It is able to complement the radiosensitivity defect of an ataxia telangiectasia (AT) fibroblast cell line. SUBUNIT: Interacts with VIM and HINT1. INTERACTION: O15169:AXIN1; NbExp=2; IntAct=EBI-702370, EBI-710484; O14641:DVL2; NbExp=5; IntAct=EBI-702370, EBI-740850; Q96CN9:GCC1; NbExp=2; IntAct=EBI-702370, EBI-746252; P49841:GSK3B; NbExp=2; IntAct=EBI-702370, EBI-373586; SUBCELLULAR LOCATION: Cytoplasm. Note=Colocalizes with intermediate filaments. TISSUE SPECIFICITY: Expressed in placenta, prostate and thymus. PTM: Constitutively phosphorylated by PKC on serine/threonine in A431 cells. SIMILARITY: Contains 1 B box-type zinc finger.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q14134
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Molecular Function: GO:0002039 p53 binding GO:0003700 transcription factor activity, sequence-specific DNA binding GO:0005515 protein binding GO:0008270 zinc ion binding GO:0042802 identical protein binding GO:0046872 metal ion binding GO:0098641 cadherin binding involved in cell-cell adhesion
Biological Process: GO:0000122 negative regulation of transcription from RNA polymerase II promoter GO:0002376 immune system process GO:0006366 transcription from RNA polymerase II promoter GO:0045087 innate immune response GO:0098609 cell-cell adhesion GO:1900181 negative regulation of protein localization to nucleus
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Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
