ID:RBPJL_HUMAN DESCRIPTION: RecName: Full=Recombining binding protein suppressor of hairless-like protein; AltName: Full=Transcription factor RBP-L; FUNCTION: Putative transcription factor, which cooperates with EBNA2 to activate transcription (By similarity). SUBUNIT: Interacts weakly with EBNA2. Does not interact with any Notch proteins (By similarity). SUBCELLULAR LOCATION: Nucleus (Probable). SIMILARITY: Belongs to the Su(H) family. SIMILARITY: Contains 1 IPT/TIG domain.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
SCOP Domains: 48726 - Immunoglobulin 81296 - E set domains 49417 - p53-like transcription factors 110217 - DNA-binding protein LAG-1 (CSL)
ModBase Predicted Comparative 3D Structure on Q9UBG7
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Molecular Function: GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding GO:0003677 DNA binding GO:0003682 chromatin binding GO:0003700 transcription factor activity, sequence-specific DNA binding
Biological Process: GO:0006351 transcription, DNA-templated GO:0006355 regulation of transcription, DNA-templated GO:0006366 transcription from RNA polymerase II promoter GO:0007165 signal transduction GO:0045893 positive regulation of transcription, DNA-templated GO:0045944 positive regulation of transcription from RNA polymerase II promoter